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Descriptor English: Basement Membrane
Descriptor Spanish: Membrana Basal
Descriptor membrana basal
Entry term(s) lámina basal
lámina densa
lámina lúcida
lámina reticular
Scope note: MATRIZ EXTRACELULAR (MEC) de aspecto oscuro y reticular que separa capas de células, como el EPITELIO del ENDOTELIO o una capa de TEJIDO CONJUNTIVO. La MEC que sirve de soporte a un EPITELIO o a un ENDOTELIO suprayacentes se denomina lámina basal. Las membranas basales (MB) pueden estar formadas por la fusión de dos láminas basales adyacentes o por la de una lámina basal con una lámina reticular adyacente de tejido conjuntivo. La membrana basal, compuesta principalmente por COLÁGENO TIPO IV, glicoproteína LAMININA y PROTEOGLICANO, sirve tanto de barrera como como de canal entre capas de células relacionadas.
Descriptor Portuguese: Membrana Basal
Descriptor French: Membrane basale
Entry term(s): Basal Lamina
Basal Laminas
Basement Lamina
Basement Laminas
Basement Membranes
Densas, Lamina
Lamina Densa
Lamina Lucida
Lamina Reticularis
Lamina, Basal
Lamina, Basement
Laminas, Basal
Laminas, Basement
Lucida, Lamina
Membrane, Basement
Membranes, Basement
Reticularis, Lamina
Tree number(s): A10.615.179
A11.284.295.310.070
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001485
Scope note: A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.
Annotation: do not confuse entry term BASAL LAMINA with "lamina basalis", the basal plate of the embryonic neural tube
Allowable Qualifiers: AB abnormalities
AH anatomy & histology
BS blood supply
CH chemistry
CY cytology
DE drug effects
DG diagnostic imaging
EM embryology
EN enzymology
GD growth & development
IM immunology
IN injuries
IR innervation
ME metabolism
MI microbiology
PA pathology
PH physiology
PP physiopathology
PS parasitology
RE radiation effects
SU surgery
TR transplantation
UL ultrastructure
VI virology
Public MeSH Note: 67
History Note: 67(65)
DeCS ID: 1507
Unique ID: D001485
NLM Classification: QS 532.5.E7
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1967/01/01
Date of Entry: 1999/01/01
Revision Date: 2023/05/22
Basement Membrane - Preferred
Concept UI M0002213
Scope note A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.
Preferred term Basement Membrane
Entry term(s) Basement Membranes
Membrane, Basement
Membranes, Basement
Basal Lamina - Narrower
Concept UI M0002215
Preferred term Basal Lamina
Entry term(s) Basal Laminas
Basement Lamina
Basement Laminas
Lamina, Basal
Lamina, Basement
Laminas, Basal
Laminas, Basement
Lamina Lucida - Narrower
Concept UI M000759377
Preferred term Lamina Lucida
Entry term(s) Lucida, Lamina
Lamina Densa - Narrower
Concept UI M000759378
Preferred term Lamina Densa
Entry term(s) Densas, Lamina
Lamina Reticularis - Narrower
Concept UI M000759379
Preferred term Lamina Reticularis
Entry term(s) Reticularis, Lamina



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