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Descriptor English: RNA Polymerase I
Descriptor Spanish: ARN Polimerasa I
Descriptor ARN polimerasa I
Entry term(s) ARN polimerasa I dependiente de ADN
RNA polimerasa I
RNA polimerasa I DNA-dependiente
RNA polimerasa I dependiente de DNA
Scope note: ARN polimerasa dependiente de ADN presente en células bacterianas, vegetales y animales. La enzima funciona en la estructura nucleolar y transcribe ADN a ARN. Tiene requerimientos para cationes y sales diferentes a los de la ARN polimerasa II y III, y no es inhibida por la alfa-amanitina.
Descriptor Portuguese: RNA Polimerase I
Descriptor French: RNA polymerase I
Entry term(s): DNA Dependent RNA Polymerase I
DNA-Dependent RNA Polymerase I
Polymerase A, RNA
Polymerase I, RNA
RNA Polymerase A
Tree number(s): D08.811.913.696.445.735.270.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012318
Scope note: A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions in the nucleolar structure and transcribes DNA into RNA. It has different requirements for cations and salts than RNA polymerase II and III and is not inhibited by alpha-amanitin.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.7.6
Previous Indexing: RNA Nucleotidyltransferases (1968-1972)
RNA Polymerases (1973-1976)
Public MeSH Note: 84; was see under RNA POLYMERASES 1977-83
History Note: 84(77); was see under RNA POLYMERASES 1977-83
DeCS ID: 21057
Unique ID: D012318
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1976/04/19
Revision Date: 2016/06/29
RNA Polymerase I - Preferred
Concept UI M0019145
Scope note A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions in the nucleolar structure and transcribes DNA into RNA. It has different requirements for cations and salts than RNA polymerase II and III and is not inhibited by alpha-amanitin.
Preferred term RNA Polymerase I
Entry term(s) DNA Dependent RNA Polymerase I
DNA-Dependent RNA Polymerase I
Polymerase A, RNA
Polymerase I, RNA
RNA Polymerase A



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