| Descriptor English: | Immunoglobulin Fc Fragments | ||||||
| Descriptor Spanish: |
Fragmentos Fc de Inmunoglobulinas
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| Descriptor Portuguese: | Fragmentos Fc das Imunoglobulinas | ||||||
| Descriptor French: | Fragments Fc des immunoglobulines | ||||||
| Entry term(s): |
Fc Fragment Fc Fragment Immunoglobulins Fc Fragment, Immunoglobulin Fc Fragments Fc Fragments, Ig Fc Fragments, Immunoglobulin Fc Immunoglobulin Fc Immunoglobulins Fragment Immunoglobulins, Fc Fragments, Ig Fc Ig Fc Fragments Immunoglobulin Fc Fragment Immunoglobulins, Fc Immunoglobulins, Fc Fragment |
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| Tree number(s): |
D12.644.541.500.697 D12.776.124.486.485.538.500 D12.776.124.486.485.680.697 D12.776.124.790.651.538.500 D12.776.124.790.651.680.660 D12.776.377.715.548.538.500 D12.776.377.715.548.680.660 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D007141 | ||||||
| Scope note: | Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PO poisoning RE radiation effects TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Pharm Action: |
Immunologic Factors |
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| Previous Indexing: |
Immunoglobulins (1970-1972) |
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| Public MeSH Note: | 2006; see IMMUNOGLOBULINS, FC 1987-2005, see IMMUNOGLOBULIN FRAGMENTS 1984-1986, see IMMUNOGLOBULINS, FC 1973-1983 |
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| History Note: | 2006 (1973) |
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| Entry Version: | IG FC FRAGMENTS |
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| Related: |
Receptors, Fc
MeSH | ||||||
| DeCS ID: | 22215 | ||||||
| Unique ID: | D007141 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1973/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2019/07/05 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Immunoglobulin Fc Fragments
- Preferred
| Concept UI |
M0011127 |
| Scope note | Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN. |
| Preferred term | Immunoglobulin Fc Fragments |
| Entry term(s) |
Fc Fragment Fc Fragment Immunoglobulins Fc Fragment, Immunoglobulin Fc Fragments Fc Fragments, Ig Fc Fragments, Immunoglobulin Fc Immunoglobulin Fc Immunoglobulins Fragment Immunoglobulins, Fc Fragments, Ig Fc Ig Fc Fragments Immunoglobulin Fc Fragment Immunoglobulins, Fc Immunoglobulins, Fc Fragment |
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