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Descriptor English: Enkephalin, Leucine
Descriptor Spanish: Encefalina Leucina
Descriptor encefalina leucina
Scope note: Tirosilglicilglicilfenilalanilleucina. Pentapéptido endógeno con actividad semejante a la morfina. El aminoácido en la posición 5 es la leucina.
Descriptor Portuguese: Encefalina Leucina
Descriptor French: Leucine-enképhaline
Entry term(s): 5 Leucine Enkephalin
5-Leucine Enkephalin
Enkephalin, 5-Leucine
Leu Enkephalin
Leu(5)-Enkephalin
Leu-Enkephalin
Leucine Enkephalin
Tree number(s): D12.644.400.575.281.231
D12.776.631.650.575.281.231
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004743
Scope note: One of the endogenous pentapeptides with morphine-like activity. It differs from MET-ENKEPHALIN in the LEUCINE at position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Neurotransmitter Agents
Registry Number: 58822-25-6
CAS Type 1 Name: Tyr-Gly-Gly-Phe-Leu
Previous Indexing: Enkephalins (Aug 1977-1982)
Nerve Tissue Proteins (1966-Jul 1977)
Peptides (1966-Jul 1977)
Public MeSH Note: 83
History Note: 83
Entry Version: ENKEPHALIN LEU
DeCS ID: 22439
Unique ID: D004743
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1983/01/01
Date of Entry: 1982/05/04
Revision Date: 2015/11/23
Enkephalin, Leucine - Preferred
Concept UI M0007454
Scope note One of the endogenous pentapeptides with morphine-like activity. It differs from MET-ENKEPHALIN in the LEUCINE at position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.
Preferred term Enkephalin, Leucine
Entry term(s) 5 Leucine Enkephalin
5-Leucine Enkephalin
Enkephalin, 5-Leucine
Leu Enkephalin
Leu(5)-Enkephalin
Leu-Enkephalin
Leucine Enkephalin



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