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Descriptor English: Selegiline
Descriptor Spanish: Selegilina
Descriptor selegilina
Entry term(s) deprenal
deprenalina
Scope note: Inhibidor selectivo e irreversible de la monoaminooxidasa tipo B que se utiliza para el tratamiento de pacientes con ENFERMEDAD DE PARKINSON recién diagnosticada y para el tratamiento de trastornos depresivos. El compuesto sin designación isomérica es el deprenilo.
Descriptor Portuguese: Selegilina
Descriptor French: Sélégiline
Entry term(s): Deprenalin
Deprenil
Deprenyl
E 250
E-250
E250
Eldepryl
Emsam
Humex
Jumex
L-Deprenyl
Selegiline Hydrochloride
Selegiline Hydrochloride, (R)-Isomer
Selegiline Hydrochloride, (R,S)-Isomer
Selegiline Hydrochloride, (S)-Isomer
Selegiline, (R)-Isomer
Selegiline, (R,S)-Isomer
Selegiline, (S)-Isomer
Selegyline
Yumex
Zelapar
Tree number(s): D02.092.471.683.915
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012642
Scope note: A selective, irreversible inhibitor of Type B monoamine oxidase that is used for the treatment of newly diagnosed patients with PARKINSON DISEASE, and for the treatment of depressive disorders. The compound without isomeric designation is Deprenyl.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antidepressive Agents
Antiparkinson Agents
Monoamine Oxidase Inhibitors
Neuroprotective Agents
Registry Number: 2K1V7GP655
CAS Type 1 Name: Benzeneethanamine, N,alpha-dimethyl-N-2-propynyl-, (R)-
Previous Indexing: Monoamine Oxidase Inhibitors (1966-1978)
Phenethylamines (1966-1978)
Public MeSH Note: 91; was see under PHENETHYLAMINES 1984-90; was DEPRENYL see under PHENETHYLAMINES 1979-83
Online Note: use SELEGILINE to search DEPRENYL 1979-83
History Note: 91(84); was see under PHENETHYLAMINES 1984-90; was DEPRENYL see under PHENETHYLAMINES 1979-83
DeCS ID: 22667
Unique ID: D012642
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/12/09
Revision Date: 2018/07/02
Selegiline - Preferred
Concept UI M0019601
Scope note A selective, irreversible inhibitor of Type B monoamine oxidase that is used for the treatment of newly diagnosed patients with PARKINSON DISEASE, and for the treatment of depressive disorders. The compound without isomeric designation is Deprenyl.
Preferred term Selegiline
Entry term(s) L-Deprenyl
Selegiline, (R)-Isomer
Selegyline
Emsam - Narrower
Concept UI M0507035
Preferred term Emsam
Selegiline Hydrochloride, (R,S)-Isomer - Narrower
Concept UI M0329706
Preferred term Selegiline Hydrochloride, (R,S)-Isomer
Selegiline Hydrochloride, (S)-Isomer - Narrower
Concept UI M0329711
Preferred term Selegiline Hydrochloride, (S)-Isomer
Eldepryl - Narrower
Concept UI M0019603
Preferred term Eldepryl
Selegiline, (S)-Isomer - Related but not broader or narrower
Concept UI M0329710
Preferred term Selegiline, (S)-Isomer
Yumex - Narrower
Concept UI M0019600
Preferred term Yumex
Entry term(s) Humex
Jumex
Zelapar - Narrower
Concept UI M0501263
Preferred term Zelapar
Deprenyl - Narrower
Concept UI M0019602
Preferred term Deprenyl
E-250 - Narrower
Concept UI M0351220
Preferred term E-250
Entry term(s) E 250
E250
Selegiline Hydrochloride, (R)-Isomer - Narrower
Concept UI M0329708
Preferred term Selegiline Hydrochloride, (R)-Isomer
Entry term(s) Selegiline Hydrochloride
Selegiline, (R,S)-Isomer - Related but not broader or narrower
Concept UI M0329712
Preferred term Selegiline, (R,S)-Isomer
Entry term(s) Deprenalin
Deprenil



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