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Descriptor English: Prenylamine
Descriptor Spanish: Prenilamina
Descriptor prenilamina
Scope note: Fármaco previamente utilizado en el tratamiento de la angina de pecho pero ha sido sustituída por otros menos peligrosos. La prenilamina agota los depósitos cardíacos de catecolaminas y tiene cierta actividad bloqueadora de los canales de calcio. (Martindale, The Extra Pharmacopoeia, 30th ed, p1406).
Descriptor Portuguese: Prenilamina
Descriptor French: Prénylamine
Entry term(s): Corontin
Difril
Segontin
Tree number(s): D02.092.471.683.825
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011299
Scope note: A drug formerly used in the treatment of angina pectoris but superseded by less hazardous drugs. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1406)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Calcium Channel Blockers
Vasodilator Agents
Adrenergic Agents
Registry Number: K2OH82Z000
CAS Type 1 Name: Benzenepropanamine, N-(1-methyl-2-phenylethyl)-gamma-phenyl-
Public MeSH Note: 66; was SEGONTIN 1963-65
History Note: 66; was SEGONTIN 1963-65
DeCS ID: 23430
Unique ID: D011299
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Prenylamine - Preferred
Concept UI M0017547
Scope note A drug formerly used in the treatment of angina pectoris but superseded by less hazardous drugs. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1406)
Preferred term Prenylamine
Difril - Narrower
Concept UI M0017546
Preferred term Difril
Segontin - Narrower
Concept UI M0017545
Preferred term Segontin
Corontin - Narrower
Concept UI M0351219
Preferred term Corontin



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