| Descriptor English: | Somatostatin | ||||||
| Descriptor Spanish: |
Somatostatina
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| Descriptor Portuguese: | Somatostatina | ||||||
| Descriptor French: | Somatostatine | ||||||
| Entry term(s): |
Cyclic Somatostatin SRIH-14 Somatofalk Somatostatin 14 Somatostatin, Cyclic Somatostatin-14 Somatotropin Release Inhibiting Factor Somatotropin Release Inhibiting Hormone Somatotropin Release-Inhibiting Factor Somatotropin Release-Inhibiting Hormone Stilamin |
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| Tree number(s): |
D06.472.699.327.700.875 D06.472.699.587.780 D12.644.400.400.700.875 D12.644.548.365.700.875 D12.644.548.586.780 D12.776.631.650.405.700.875 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D013004 | ||||||
| Scope note: | A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Hormones |
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| Registry Number: | 51110-01-1 | ||||||
| Previous Indexing: |
Somatotropin Releasing Hormone/antagonists & inhibitors (1974) Somatotropin/antagonists & inhibitors (1973-1974) |
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| Public MeSH Note: | 99 |
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| Online Note: | use SOMATOSTATIN to search SOMATOTROPIN RELEASE INHIBITING HORMONE 1975-84 |
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| History Note: | 99 |
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| Related: |
Receptors, Somatostatin
MeSH | ||||||
| DeCS ID: | 22676 | ||||||
| Unique ID: | D013004 | ||||||
| NLM Classification: | WK 515 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1975/09/01 | ||||||
| Date of Entry: | 1974/11/11 | ||||||
| Revision Date: | 2015/11/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
|
|
Somatostatin
- Preferred
Stilamin
- Narrower
Somatofalk
- Narrower
| Concept UI |
M0020152 |
| Scope note | A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal. |
| Preferred term | Somatostatin |
| Entry term(s) |
Cyclic Somatostatin SRIH-14 Somatostatin 14 Somatostatin, Cyclic Somatostatin-14 Somatotropin Release Inhibiting Factor Somatotropin Release Inhibiting Hormone Somatotropin Release-Inhibiting Factor Somatotropin Release-Inhibiting Hormone |
| Concept UI |
M0020154 |
| Preferred term | Stilamin |
| Concept UI |
M0020153 |
| Preferred term | Somatofalk |
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