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Descriptor English: Prodrugs
Descriptor Spanish: Profármacos
Descriptor Portuguese: Pró-Fármacos
Descriptor French: Promédicaments
Entry term(s): Drug Precursors
Precursors, Drug
Pro Drugs
Pro-Drugs
Tree number(s): D26.675
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011355
Scope note: A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
Annotation: coordinate with specific drug
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
Previous Indexing: Delayed-Action Preparations (1966-1987)
Public MeSH Note: 89; was see under DRUGS 1988
History Note: 89(88); was see under DRUGS 1988
DeCS ID: 22970
Unique ID: D011355
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1987/05/04
Revision Date: 2003/07/09
Prodrugs - Preferred
Concept UI M0017642
Scope note A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
Preferred term Prodrugs
Entry term(s) Drug Precursors
Precursors, Drug
Pro Drugs
Pro-Drugs



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