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Descriptor English: Affinity Labels
Descriptor Spanish: Marcadores de Afinidad
Descriptor marcadores de afinidad
Entry term(s) etiquetas de afinidad
reactivos de etiquetas de afinidad
Scope note: Análogos de sustratos o compuestos que se unen naturalmente a los sitios activos de proteínas, enzimas, anticuerpos, esteroides o receptores fisiológicos. Estos análogos forman un enlace covalente estable en el sitio de unión, actuando en consecuencia como inhibidores de las proteínas o los esteroides.
Descriptor Portuguese: Marcadores de Afinidade
Descriptor French: Marqueurs d'affinité
Entry term(s): Affinity Labeling Reagents
Labeling Reagents, Affinity
Labels, Affinity
Reagents, Affinity Labeling
Tree number(s): D27.720.470.410.080
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000345
Scope note: Analogs of those substrates or compounds which bind naturally at the active sites of proteins, enzymes, antibodies, steroids, or physiological receptors. These analogs form a stable covalent bond at the binding site, thereby acting as inhibitors of the proteins or steroids.
Annotation: D25-26 qualif; use with caution: few apply
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
Previous Indexing: Binding Sites (1968-1974)
Indicators and Reagents (1968-1974)
Public MeSH Note: 75
History Note: 75
DeCS ID: 23088
Unique ID: D000345
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1975/09/01
Date of Entry: 1974/11/19
Revision Date: 2003/07/09
Affinity Labels - Preferred
Concept UI M0000530
Scope note Analogs of those substrates or compounds which bind naturally at the active sites of proteins, enzymes, antibodies, steroids, or physiological receptors. These analogs form a stable covalent bond at the binding site, thereby acting as inhibitors of the proteins or steroids.
Preferred term Affinity Labels
Entry term(s) Affinity Labeling Reagents
Labeling Reagents, Affinity
Labels, Affinity
Reagents, Affinity Labeling



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