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Descriptor English: KB Cells
Descriptor Spanish: Células KB
Descriptor células KB
Scope note: En la actualidad se sabe que esta línea KB es una sublínea de la omnipresente HeLa, línea celular tumoral formadora de QUERATINA. Originalmente se pensó que derivaba del carcinoma epidérmico de la boca, pero luego se descubrió, basándose en el análisis isoenzimático, que los marcadores cromosómicos HeLa y la huella de ADN procedían de la contaminación por CÉLULAS HELA. Las células son positivas para la queratina mediante la tinción con inmunoperoxidasa. Se han descrito células KB que contienen secuencias del papilomavirus humano 18 (VPH-18).
Descriptor Portuguese: Células KB
Descriptor French: Cellules KB
Entry term(s): Cell, HeLa-KB
Cell, KB
Cells, HeLa-KB
Cells, KB
HeLa KB Cells
HeLa-KB Cell
HeLa-KB Cells
KB Cell
Tree number(s): A11.251.210.190.400.500
A11.251.860.180.400.500
A11.436.340.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007624
Scope note: This line KB is now known to be a subline of the ubiquitous KERATIN-forming tumor cell line HeLa. It was originally thought to be derived from an epidermal carcinoma of the mouth, but was subsequently found, based on isoenzyme analysis, HeLa marker chromosomes, and DNA fingerprinting, to have been established via contamination by HELA CELLS. The cells are positive for keratin by immunoperoxidase staining. KB cells have been reported to contain human papillomavirus18 (HPV-18) sequences.
Annotation: almost always NIM with no subheadings; check HUMAN; do not routinely add neoplasm term
Allowable Qualifiers: CH chemistry
CL classification
CY cytology
DE drug effects
EN enzymology
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Previous Indexing: Cell Line (1969-1984)
Tissue Culture (1966-1971)
Public MeSH Note: 85
History Note: 85
DeCS ID: 23293
Unique ID: D007624
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1985/01/01
Date of Entry: 1984/04/05
Revision Date: 2005/06/30
KB Cells - Preferred
Concept UI M0011933
Scope note This line KB is now known to be a subline of the ubiquitous KERATIN-forming tumor cell line HeLa. It was originally thought to be derived from an epidermal carcinoma of the mouth, but was subsequently found, based on isoenzyme analysis, HeLa marker chromosomes, and DNA fingerprinting, to have been established via contamination by HELA CELLS. The cells are positive for keratin by immunoperoxidase staining. KB cells have been reported to contain human papillomavirus18 (HPV-18) sequences.
Preferred term KB Cells
Entry term(s) Cell, HeLa-KB
Cell, KB
Cells, HeLa-KB
Cells, KB
HeLa KB Cells
HeLa-KB Cell
HeLa-KB Cells
KB Cell



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