| Descriptor in English: | Cardenolides |
| Descriptor in Spanish: | Cardenólidos |
| Descriptor in Portuguese: | Cardenolídeos |
| Descriptor in French: | Cardénolides |
| Tree number(s): |
D04.210.500.155.580.130 |
| Scope note: | C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS. |
| Annotation: | includes cardadienolides & cardatrienolides; do not confuse with CARDANOLIDES |
| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
| History Note: | 77 |
| DeCS UI: | 2342 |
| Descriptor UI: | D002298 |
| Date Established: | 1977/01/01 |
| Date of Entry: | 1976/04/16 |
| Revision Date: | 2016/05/27 |
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CHEMICALS AND DRUGS
Polycyclic Compounds [D04]Polycyclic Compounds
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Cardenolides
- Preferred
| Concept UI |
M0003448 |
| Scope note | C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS. |
| Preferred term | Cardenolides |
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