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Descriptor in English: Cardenolides
Descriptor in Spanish: Cardenólidos
Descriptor in Portuguese: Cardenolídeos
Descriptor in French: Cardénolides
Tree number(s): D04.210.500.155.580.130
Scope note: C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.
Annotation: includes cardadienolides & cardatrienolides; do not confuse with CARDANOLIDES
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 77
DeCS UI: 2342
Descriptor UI: D002298
Date Established: 1977/01/01
Date of Entry: 1976/04/16
Revision Date: 2016/05/27
Cardenolides - Preferred
Concept UI M0003448
Scope note C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.
Preferred term Cardenolides



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