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Descriptor English: Tubercidin
Descriptor Spanish: Tubercidina
Descriptor tubercidina
Entry term(s) 7-desazaadenosina
Scope note: Antibiótico ribonucleósido purínico que se sustituye fácilmente por adenosina en el sistema biológico, pero su incorporación en el ADN y el ARN tiene efecto inhibidor sobre el metabolismo de estos ácidos nucleicos.
Descriptor Portuguese: Tubercidina
Descriptor French: Tubercidine
Entry term(s): 4-Amino-7 beta-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine
7 Deazaadenosine
7-Deazaadenosine
Deazaadenosine
Tree number(s): D03.633.100.759.590.910
D13.570.583.910
D13.570.800.850
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D014372
Scope note: An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids.
Annotation: an antineoplastic antimetabolite
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Antimetabolites, Antineoplastic
Registry Number: M351LCX45Y
CAS Type 1 Name: 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, 7-beta-D-ribofuranosyl-
Previous Indexing: Pyrimidines (1973-1974)
Pyrroles (1973-1974)
Ribonucleosides (1973-1974)
Public MeSH Note: 91; was see under ANTIBIOTICS, AMINOGLYCOSIDE 1975-90
History Note: 91(75); was see under ANTIBIOTICS, AMINOGLYCOSIDE 1975-90
DeCS ID: 23494
Unique ID: D014372
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2016/06/01
Tubercidin - Preferred
Concept UI M0022097
Scope note An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids.
Preferred term Tubercidin
Entry term(s) 4-Amino-7 beta-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine
7 Deazaadenosine
7-Deazaadenosine
Deazaadenosine



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