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Descriptor English: Site-Specific DNA-Methyltransferase (Adenine-Specific)
Descriptor Spanish: Metiltransferasa de ADN de Sitio Específico (Adenina Especifica)
Descriptor ADN metiltransferasa específica de sitio (específicas de adenina)
Entry term(s) ADN-adenina metilasas
metilasas de modificación (específicas de adenina)
metilasas de modificación de ADN (específicas de adenina)
metiltransferasas específicas de sitio (específicas de adenina)
Scope note: Enzima responsable de la producción de un patrón de metilación característico de la especie en los residuos de adenina, en una secuencia de bases corta y específica en el ADN de la célula huésped. La enzima cataliza la metilación de la adenina del ADN en presencia de S-adenosil-L-metionina para formar ADN con 6-metilaminopurina y S-adenosil-L-homocisteína. EC 2.1.1.72.
Descriptor Portuguese: DNA Metiltransferases Sítio Específica (Adenina-Específica)
Descriptor French: Site-specific DNA-methyltransferase (adenine-specific)
Entry term(s): DNA Adenine Methylases
DNA Modification Methylases (Adenine-Specific)
DNA Modification Methylases Adenine Specific
DNA-Adenine Methylases
Methylases, DNA-Adenine
Modification Methylases (Adenine Specific)
Modification Methylases (Adenine-Specific)
Site Specific Methyltransferases (Adenine Specific)
Site-Specific Methyltransferases (Adenine-Specific)
Tree number(s): D08.811.913.555.500.350.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015265
Scope note: An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyzes the methylation of DNA adenine in the presence of S-adenosyl-L-methionine to form DNA containing 6-methylaminopurine and S-adenosyl-L-homocysteine. EC 2.1.1.72.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.1.1.72
Previous Indexing: Methyltransferases (1971-1988)
Public MeSH Note: 98; see DNA MODIFICATION METHYLASES (ADENINE-SPECIFIC) 1989-97
History Note: 98(89)
DeCS ID: 23614
Unique ID: D015265
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/05/18
Revision Date: 2003/07/09
Site-Specific DNA-Methyltransferase (Adenine-Specific) - Preferred
Concept UI M0023504
Scope note An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyzes the methylation of DNA adenine in the presence of S-adenosyl-L-methionine to form DNA containing 6-methylaminopurine and S-adenosyl-L-homocysteine. EC 2.1.1.72.
Preferred term Site-Specific DNA-Methyltransferase (Adenine-Specific)
Entry term(s) DNA Adenine Methylases
DNA Modification Methylases (Adenine-Specific)
DNA Modification Methylases Adenine Specific
DNA-Adenine Methylases
Methylases, DNA-Adenine
Modification Methylases (Adenine Specific)
Modification Methylases (Adenine-Specific)
Site Specific Methyltransferases (Adenine Specific)
Site-Specific Methyltransferases (Adenine-Specific)



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