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Descriptor English: RNA Probes
Descriptor Spanish: Sondas ARN
Descriptor sondas de ARN
Entry term(s) sonda de ARN
sondas de ARN de genes
Scope note: ARN que suele producirse por transcripción de ADN clonado, el cual es complementario de un ARNm o ADN específico y que se usa generalmente en el estudio de genes víricos, de la distribución de ARN específico en tejidos y células, la integración del ADN vírico en genomas, la transcripción, etcétera. Aunque es preferible usar las SONDAS DE ADN en un nivel más macroscópico para detectar la presencia de ADN/ARN de especies o subespecies específicas, en los estudios genéticos se prefieren las sondas de ARN. Las sondas suelen marcarse con los radioisótopos 32P y 125I, y con el marcador químico biotina. Las sondas de ARN pueden dividirse por categorías en sondas ARN de sentido +, sondas ARN de sentido - y sondas de ARN antisentido.
Descriptor Portuguese: Sondas RNA
Descriptor French: Sondes d'ARN
Entry term(s): Gene Probes, RNA
Probe, RNA
Probes, RNA
Probes, RNA Gene
RNA Gene Probes
RNA Probe
Tree number(s): D13.444.600.723
D27.505.259.750.600.825
D27.720.470.530.600.825
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015347
Scope note: RNA, usually prepared by transcription from cloned DNA, which complements a specific mRNA or DNA and is generally used for studies of virus genes, distribution of specific RNA in tissues and cells, integration of viral DNA into genomes, transcription, etc. Whereas DNA PROBES are preferred for use at a more macroscopic level for detection of the presence of DNA/RNA from specific species or subspecies, RNA probes are preferred for genetic studies. Conventional labels for the RNA probe include radioisotope labels 32P and 125I and the chemical label biotin. RNA probes may be further divided by category into plus-sense RNA probes, minus-sense RNA probes, and antisense RNA probes.
Annotation: usually no qualif: /drug eff /ultrastruct permitted
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Nucleic Acid Hybridization (1972-1988)
RNA, Messenger (1972-1988)
Public MeSH Note: 89
History Note: 89
DeCS ID: 23820
Unique ID: D015347
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/06/02
Revision Date: 2020/06/25
RNA Probes - Preferred
Concept UI M0023632
Scope note RNA, usually prepared by transcription from cloned DNA, which complements a specific mRNA or DNA and is generally used for studies of virus genes, distribution of specific RNA in tissues and cells, integration of viral DNA into genomes, transcription, etc. Whereas DNA PROBES are preferred for use at a more macroscopic level for detection of the presence of DNA/RNA from specific species or subspecies, RNA probes are preferred for genetic studies. Conventional labels for the RNA probe include radioisotope labels 32P and 125I and the chemical label biotin. RNA probes may be further divided by category into plus-sense RNA probes, minus-sense RNA probes, and antisense RNA probes.
Preferred term RNA Probes
Entry term(s) Gene Probes, RNA
Probe, RNA
Probes, RNA
Probes, RNA Gene
RNA Gene Probes
RNA Probe



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