| Descriptor English: | Norfloxacin | ||||||
| Descriptor Spanish: |
Norfloxacino
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| Descriptor Portuguese: | Norfloxacino | ||||||
| Descriptor French: | Norfloxacine | ||||||
| Entry term(s): |
AM 0715 AM 715 AM-0715 AM-715 AM0715 MK 0366 MK 366 MK-0366 MK-366 MK0366 MK366 Noroxin |
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| Tree number(s): |
D03.633.100.810.835.830.250.374 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D009643 | ||||||
| Scope note: | A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Anti-Bacterial Agents Topoisomerase II Inhibitors Cytochrome P-450 CYP1A2 Inhibitors |
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| Registry Number: | N0F8P22L1P | ||||||
| CAS Type 1 Name: | 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)- | ||||||
| Previous Indexing: |
Anti-Infective Agents (1966-1985) Anti-Infective Agents, Urinary (1966-1985) Nalidixic Acid (1966-1985) |
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| Public MeSH Note: | 86 |
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| History Note: | 86 |
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| DeCS ID: | 24350 | ||||||
| Unique ID: | D009643 | ||||||
| NLM Classification: | QV 250 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1986/01/01 | ||||||
| Date of Entry: | 1985/06/06 | ||||||
| Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Norfloxacin
- Preferred
MK-0366
- Narrower
Noroxin
- Narrower
AM-0715
- Narrower
| Concept UI |
M0014980 |
| Scope note | A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE. |
| Preferred term | Norfloxacin |
| Concept UI |
M0353994 |
| Preferred term | MK-0366 |
| Entry term(s) |
MK 0366 MK 366 MK-366 MK0366 MK366 |
| Concept UI |
M0501247 |
| Preferred term | Noroxin |
| Concept UI |
M0353993 |
| Preferred term | AM-0715 |
| Entry term(s) |
AM 0715 AM 715 AM-715 AM0715 |
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