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Descriptor English: 4-Quinolones
Descriptor Spanish: 4-Quinolonas
Descriptor 4-quinolonas
Entry term(s) 4-oxoquinolina
4-quinolinona
4-quinolona
Scope note: QUINOLONAS con un grupo 4-oxo (carbonilo en posición para en relación con el nitrógeno). Estos compuestos inhiben la subunidad A de la ADN GIRASA y se utilizan como antimicrobianos. La segunda generación de 4-quinolonas también poseen un grupo 1-piperacinilo en la posición 7 y un flúor en la posición 6.
Descriptor Portuguese: 4-Quinolonas
Descriptor French: 4-Quinolones
Entry term(s): 4 Oxoquinoline
4 Oxoquinolines
4 Quinolinone
4 Quinolinones
4 Quinolone
4 Quinolones
4-Oxoquinoline
4-Oxoquinolines
4-Quinolinone
4-Quinolinones
4-Quinolone
Tree number(s): D03.633.100.810.835.830
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D042462
Scope note: QUINOLONES containing a 4-oxo (a carbonyl in the para position to the nitrogen). They inhibit the A subunit of DNA GYRASE and are used as antimicrobials. Second generation 4-quinolones are also substituted with a 1-piperazinyl group at the 7-position and a fluorine at the 6-position.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 2004
History Note: 2004
DeCS ID: 38097
Unique ID: D042462
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2020/05/27
4-Quinolones - Preferred
Concept UI M0441453
Scope note QUINOLONES containing a 4-oxo (a carbonyl in the para position to the nitrogen). They inhibit the A subunit of DNA GYRASE and are used as antimicrobials. Second generation 4-quinolones are also substituted with a 1-piperazinyl group at the 7-position and a fluorine at the 6-position.
Preferred term 4-Quinolones
Entry term(s) 4 Oxoquinoline
4 Oxoquinolines
4 Quinolinone
4 Quinolinones
4 Quinolone
4 Quinolones
4-Oxoquinoline
4-Oxoquinolines
4-Quinolinone
4-Quinolinones
4-Quinolone



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