Descriptor English: | Giant Cells | ||||||
Descriptor Spanish: |
Células Gigantes
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Descriptor Portuguese: | Células Gigantes | ||||||
Descriptor French: | Cellules géantes | ||||||
Entry term(s): |
Cell, Giant Cell, Multinucleated Giant Cells, Giant Cells, Multinucleated Giant Giant Cell Giant Cell, Multinucleated Giant Cells, Multinucleated Multinucleated Giant Cell Multinucleated Giant Cells Polykaryocyte Polykaryocytes Syncytia Syncytium |
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Tree number(s): |
A11.500 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015726 | ||||||
Scope note: | Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus. |
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Allowable Qualifiers: |
CH chemistry CL classification CY cytology DE drug effects EN enzymology IM immunology ME metabolism MI microbiology PA pathology PH physiology PS parasitology RE radiation effects TR transplantation UL ultrastructure VI virology |
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Previous Indexing: |
Cell Fusion (1972-1989) |
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Public MeSH Note: | 90 |
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History Note: | 90 |
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DeCS ID: | 24694 | ||||||
Unique ID: | D015726 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1990/01/01 | ||||||
Date of Entry: | 1989/04/07 | ||||||
Revision Date: | 2011/06/24 |
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ANATOMY
Cells [A11]Cells
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Giant Cells
- Preferred
Concept UI |
M0024113 |
Scope note | Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus. |
Preferred term | Giant Cells |
Entry term(s) |
Cell, Giant Cell, Multinucleated Giant Cells, Giant Cells, Multinucleated Giant Giant Cell Giant Cell, Multinucleated Giant Cells, Multinucleated Multinucleated Giant Cell Multinucleated Giant Cells Polykaryocyte Polykaryocytes Syncytia Syncytium |
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