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Descriptor English: Giant Cells, Langhans
Descriptor Spanish: Células Gigantes de Langhans
Descriptor Portuguese: Células Gigantes de Langhans
Descriptor French: Cellules géantes de Langhans
Entry term(s): Cells, Langhans Giant
Cells, Langhans-Type Giant
Giant Cells, Langhans-Type
Langhans Giant Cells
Langhans Type Giant Cells
Langhans-Type Giant Cells
Tree number(s): A11.329.372.380
A11.500.380
A11.627.482.380
A11.733.397.380
A15.382.670.522.380
A15.382.680.397.380
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015744
Scope note: Multinucleated cells (fused macrophages) seen in granulomatous inflammations such as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans giant cells occur frequently in delayed hypersensitivity.
Annotation: do not confuse with LANGERHANS CELLS nor with ISLETS OF LANGERHANS
Allowable Qualifiers: CH chemistry
CL classification
CY cytology
DE drug effects
EN enzymology
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Previous Indexing: Granuloma, Giant Cell (1977-1989)
Macrophages (1966-1989)
Public MeSH Note: 91; was see under GIANT CELLS 1990
History Note: 91(90); was see under GIANT CELLS 1990
DeCS ID: 24696
Unique ID: D015744
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1989/04/07
Revision Date: 2018/06/30
Giant Cells, Langhans - Preferred
Concept UI M0024133
Scope note Multinucleated cells (fused macrophages) seen in granulomatous inflammations such as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans giant cells occur frequently in delayed hypersensitivity.
Preferred term Giant Cells, Langhans
Entry term(s) Cells, Langhans Giant
Cells, Langhans-Type Giant
Giant Cells, Langhans-Type
Langhans Giant Cells
Langhans Type Giant Cells
Langhans-Type Giant Cells



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