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Descriptor English: Centrifugation, Isopycnic
Descriptor Spanish: Centrifugación Isopicnica
Descriptor centrifugación isopícnica
Entry term(s) centrifugado isopícnico
Scope note: Técnica utilizada para separar partículas según sus densidades en un gradiente continuo de densidad. Generalmente se mezcla la muestra con una solución de materiales con gradiente conocido y se somete a centrifugación. Cada partícula sedimenta en la posición en la que el gradiente de densidad es igual a ella. El rango del gradiente de densidad es generalmente mayor que el de las partículas de la muestra. Este método se utiliza para la purificación biológica de materiales como proteínas, ácidos nucleicos, orgánulos y tipos celulares.
Descriptor Portuguese: Centrifugação Isopícnica
Descriptor French: Centrifugation isopycnique
Entry term(s): Isopycnic Centrifugation
Tree number(s): E05.181.724.336.253
E05.196.941.336.253
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002500
Scope note: A technique used to separate particles according to their densities in a continuous density gradient. The sample is usually mixed with a solution of known gradient materials and subjected to centrifugation. Each particle sediments to the position at which the gradient density is equal to its own. The range of the density gradient is usually greater than that of the sample particles. It is used in purifying biological materials such as proteins, nucleic acids, organelles, and cell types.
Allowable Qualifiers: CL classification
EC economics
ES ethics
HI history
IS instrumentation
MT methods
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Public MeSH Note: 91; was see under CENTRIFUGATION, DENSITY GRADIENT 1975-90
Online Note: search CENTRIFUGATION, DENSITY GRADIENT 1968-74
History Note: 91(75); was see under CENTRIFUGATION, DENSITY GRADIENT 1975-90
DeCS ID: 2535
Unique ID: D002500
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2002/07/03
Centrifugation, Isopycnic - Preferred
Concept UI M0003812
Scope note A technique used to separate particles according to their densities in a continuous density gradient. The sample is usually mixed with a solution of known gradient materials and subjected to centrifugation. Each particle sediments to the position at which the gradient density is equal to its own. The range of the density gradient is usually greater than that of the sample particles. It is used in purifying biological materials such as proteins, nucleic acids, organelles, and cell types.
Preferred term Centrifugation, Isopycnic
Entry term(s) Isopycnic Centrifugation



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