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Descriptor English: Cerebroside-Sulfatase
Descriptor Spanish: Cerebrósido Sulfatasa
Descriptor cerebrósido-sulfatasa
Entry term(s) arilsulfatasa A
sulfatidato sulfatasa
Scope note: Enzima que cataliza la hidrólisis de cerebrósido 3-sulfato (sulfátido) para dar lugar a un cerebrósido y sulfato inorgánico. En todas las formas de LEUCODISTROFIA METACROMÁTICA se ha evidenciado una deficiencia marcada de arilsulfatasa A, a la que se considera el componente termolábil de la cerebrósido sulfatasa. EC 3.1.6.8.
Descriptor Portuguese: Cerebrosídeo Sulfatase
Descriptor French: Cerebroside-sulfatase
Entry term(s): Arylsulfatase A
Cerebroside Sulfatase
Sulfatase, Sulfatidate
Sulfatidate Sulfatase
Tree number(s): D08.811.277.352.827.070.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002553
Scope note: An enzyme that catalyzes the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase A, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.8.
Annotation: /defic: consider also LEUKODYSTROPHY, METACHROMATIC
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.6.8
CAS Type 1 Name: Cerebroside-3-sulfate 3-sulfohydrolase
Previous Indexing: Arylsulfatases (1975)
Sulfatases (1972-1974)
Public MeSH Note: 87; was see under SULFATASES 1976-86
History Note: 87(76); was see under SULFATASES 1976-86
Related: Leukodystrophy, Metachromatic MeSH
DeCS ID: 2592
Unique ID: D002553
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1975/07/25
Revision Date: 2003/07/09
Cerebroside-Sulfatase - Preferred
Concept UI M0003905
Scope note An enzyme that catalyzes the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase A, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.8.
Preferred term Cerebroside-Sulfatase
Entry term(s) Arylsulfatase A
Cerebroside Sulfatase
Sulfatase, Sulfatidate
Sulfatidate Sulfatase



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