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Descriptor English: Cerulenin
Descriptor Spanish: Cerulenina
Descriptor cerulenina
Scope note: Epoxidodecadienamida que se obtiene a partir de diversas especies, como ACREMONIUM, Acrocylindrum, y Helicoceras. Inhibe la biosíntesis de diversos lípidos al interferir con la función enzimática.
Descriptor Portuguese: Cerulenina
Descriptor French: Cérulénine
Entry term(s): 2,3-Epoxy-4-oxo-7,10-dodecadienoylamide
Tree number(s): D02.065.327
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002569
Scope note: An epoxydodecadienamide isolated from several species, including ACREMONIUM, Acrocylindrum, and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function.
Annotation: do not confuse with CERULEIN see CERULETIDE
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antifungal Agents
Fatty Acid Synthesis Inhibitors
Registry Number: 17397-89-6
CAS Type 1 Name: Oxiranecarboxamide, 3-(1-oxo-4,7-nonadienyl)-, (2R-(2alpha,3alpha(4E,7E)))-
Previous Indexing: Antibiotics, Antifungal (1973-1974)
Ethers, Cyclic (1973-1974)
Fatty Acids, Unsaturated (1974)
Public MeSH Note: 91; was see under ANTIBIOTICS, ANTIFUNGAL 1975-90
History Note: 91(75); was see under ANTIBIOTICS, ANTIFUNGAL 1975-90
DeCS ID: 2609
Unique ID: D002569
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2013/07/10
Cerulenin - Preferred
Concept UI M0003925
Scope note An epoxydodecadienamide isolated from several species, including ACREMONIUM, Acrocylindrum, and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function.
Preferred term Cerulenin
Entry term(s) 2,3-Epoxy-4-oxo-7,10-dodecadienoylamide



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