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Descriptor English: Adenylyl Imidodiphosphate
Descriptor Spanish: Adenilil Imidodifosfato
Descriptor imidodifosfato de adenililo
Entry term(s) ATP gamma-imino
ATP gammaimino
adenil imidodifosfato
gamma imino-ATP
gamma-imino-ATP
gammaimino-ATP
imidodifosfato de adenilo
Scope note: Ácido 5'-adenílico, monoanhídrido con ácido imidodifosfórico. Análogo del ATP, en el que el átomo de oxígeno que hace de puente entre el fosfato beta y gamma es reemplazado por un átomo de nitrógeno. Es un potente inhibidor competitivo de la ATPasa mitocondrial soluble y unida a la membrana, y tambien inhibe las reacciones de fosforilación oxidativa dependientes del ATP.
Descriptor Portuguese: Adenilil Imidodifosfato
Descriptor French: Adenylyl imidodiphosphate
Entry term(s): AMP-PNP
AMP-PNP, Mg
AMPPNP
ATP(beta,gamma-NH)
Adenosine 5'-(beta,gamma-Imino)triphosphate
Adenyl Imidodiphosphate
Adenylimidodiphosphate
Adenylylimidodiphosphate
Imidodiphosphate, Adenyl
Imidodiphosphate, Adenylyl
Mg 5' Adenylylimidodiphosphate
Mg AMP PNP
Mg AMP-PNP
Mg-5'-Adenylylimidodiphosphate
beta,gamma imido ATP
beta,gamma-imido-ATP
gamma Imido ATP
gamma Imino ATP
gamma-Imido-ATP
gamma-Imino-ATP
Tree number(s): D03.633.100.759.646.138.236.050
D13.695.667.138.236.050
D13.695.827.068.236.050
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000266
Scope note: 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 25612-73-1
CAS Type 1 Name: 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid
Previous Indexing: Adenosine Diphosphate (1973-1974)
Adenosine Triphosphate/analogs & derivatives (1975)
Imides (1973-1975)
Phosphoric Acids (1973-1974)
Public MeSH Note: 91; was see under ADENOSINE TRIPHOSPHATE 1976-90
History Note: 91(76); was see under ADENOSINE TRIPHOSPHATE 1976-90
Entry Version: APPNHP
DeCS ID: 273
Unique ID: D000266
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1975/07/23
Revision Date: 2016/05/27
Adenylyl Imidodiphosphate - Preferred
Concept UI M0000416
Scope note 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation.
Preferred term Adenylyl Imidodiphosphate
Entry term(s) AMP-PNP
AMPPNP
ATP(beta,gamma-NH)
Adenosine 5'-(beta,gamma-Imino)triphosphate
Adenyl Imidodiphosphate
Adenylimidodiphosphate
Adenylylimidodiphosphate
Imidodiphosphate, Adenyl
Imidodiphosphate, Adenylyl
beta,gamma imido ATP
beta,gamma-imido-ATP
gamma Imido ATP
gamma Imino ATP
gamma-Imido-ATP
gamma-Imino-ATP
Mg-5'-Adenylylimidodiphosphate - Narrower
Concept UI M0000417
Preferred term Mg-5'-Adenylylimidodiphosphate
Entry term(s) AMP-PNP, Mg
Mg 5' Adenylylimidodiphosphate
Mg AMP PNP
Mg AMP-PNP



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