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Descriptor English: | Chlormethiazole | ||||
Descriptor Spanish: |
Clormetiazol
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Descriptor Portuguese: | Clormetiazol | ||||
Descriptor French: | Clométhiazole | ||||
Tree number(s): |
D02.886.675.180 D03.383.129.708.180 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D002719 | ||||
Scope note: | A sedative and anticonvulsant often used in the treatment of alcohol withdrawal. Chlormethiazole has also been proposed as a neuroprotective agent. The mechanism of its therapeutic activity is not entirely clear, but it does potentiate GAMMA-AMINOBUTYRIC ACID receptors response and it may also affect glycine receptors. |
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Allowable Qualifiers: |
AA analogues et dérivés AD administration et posologie AE effets indésirables AG agonistes AI antagonistes et inhibiteurs AN analyse BL sang CF liquide cérébrospinal CH composition chimique CL classification CS synthèse chimique EC économie HI histoire IM immunologie IP isolement et purification ME métabolisme PD pharmacologie PK pharmacocinétique PO intoxication RE effets des radiations SD ressources et distribution ST normes TO toxicité TU usage thérapeutique UR urine |
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Pharm Action: |
Anticonvulsants Hypnotics and Sedatives Neuroprotective Agents GABA Modulators |
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Registry Number: | 0C5DBZ19HV | ||||
CAS Type 1 Name: | Thiazole, 5-(2-chloroethyl)-4-methyl- | ||||
DeCS ID: | 2764 | ||||
Unique ID: | D002719 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 1968/01/01 | ||||
Date of Entry: | 1999/01/01 | ||||
Revision Date: | 2016/05/28 |
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PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés chimiques organiques [D02]Composés chimiques organiques -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés hétérocycliques [D03]Composés hétérocycliques
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