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Descriptor English: Ritonavir
Descriptor Spanish: Ritonavir
Descriptor Portuguese: Ritonavir
Descriptor French: Ritonavir
Entry term(s): ABT 538
ABT-538
ABT538
Norvir
Tree number(s): D02.886.675.653
D03.383.129.708.653
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019438
Scope note: An HIV protease inhibitor that works by interfering with the reproductive cycle of HIV. It also inhibits CYTOCHROME P-450 CYP3A.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: HIV Protease Inhibitors
Cytochrome P-450 CYP3A Inhibitors
Registry Number: O3J8G9O825
Previous Indexing: HIV Protease Inhibitors (1995)
Thiazoles (1996)
Valine/analogs & derivatives (1996)
Public MeSH Note: 97; ABT 538 was indexed under THIAZOLES & VALINE/analogs & derivatives 1996 & HIV PROTEASE INHIBITORS 1995
Online Note: use RITONAVIR (NM) to search ABT 538 1995-96
History Note: 97; was ABT 538 (NM) 1995-96
DeCS ID: 32994
Unique ID: D019438
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2016/07/01
Ritonavir - Preferred
Concept UI M0028918
Scope note An HIV protease inhibitor that works by interfering with the reproductive cycle of HIV. It also inhibits CYTOCHROME P-450 CYP3A.
Preferred term Ritonavir
ABT 538 - Narrower
Concept UI M0373924
Preferred term ABT 538
Entry term(s) ABT-538
ABT538
Norvir - Narrower
Concept UI M0028919
Preferred term Norvir



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