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Descriptor English: Lurasidone Hydrochloride
Descriptor Spanish: Clorhidrato de Lurasidona
Descriptor clorhidrato de lurasidona
Scope note: Derivado del tiazol y ANTIPSICÓTICO atípico que funciona como ANTAGONISTA DEL RECEPTOR DE DOPAMINA D2, ANTAGONISTA DEL RECEPTOR DE SEROTONINA 5-HT2, antagonista del receptor de serotonina 5-HT7 y antagonista de los receptores adrenérgicos alfa2A y alfa2C, y AGONISTA DEL RECEPTOR DE SEROTONINA 5-HT1A (agonista parcial). Se utiliza en el tratamiento de la ESQUIZOFRENIA y del TRASTORNO BIPOLAR.
Descriptor Portuguese: Cloridrato de Lurasidona
Descriptor French: Chlorhydrate de lurasidone
Entry term(s): 13496, SM
HCl, Lurasidone
Hydrochloride, Lurasidone
Latuda
Lurasidone
Lurasidone HCl
N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide
SM 13,496
SM 13496
SM-13,496
SM-13496
SM13,496
SM13496
Tree number(s): D02.886.675.414
D03.383.129.708.414
D03.633.100.513.437
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069056
Scope note: A thiazole derivative and atypical ANTIPSYCHOTIC AGENT that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST; SEROTONIN 5-HT2 RECEPTOR ANTAGONIST, serotonin 5-HT7 receptor antagonist, and antagonist of the adrenergic α2A and α2C receptors, as well as a partial SEROTONIN 5-HT1A RECEPTOR AGONIST. It is used in the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antipsychotic Agents
Adrenergic alpha-2 Receptor Antagonists
Serotonin 5-HT2 Receptor Antagonists
Dopamine D2 Receptor Antagonists
Registry Number: O0P4I5851I
Public MeSH Note: 2016; LURASIDONE HYDROCHLORIDE was indexed under ISOINDOLES and THIAZOLES 2008-2015
History Note: 2016 (2008)
DeCS ID: 55906
Unique ID: D000069056
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/09
Revision Date: 2016/05/31
Lurasidone Hydrochloride - Preferred
Concept UI M000604584
Scope note A thiazole derivative and atypical ANTIPSYCHOTIC AGENT that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST; SEROTONIN 5-HT2 RECEPTOR ANTAGONIST, serotonin 5-HT7 receptor antagonist, and antagonist of the adrenergic α2A and α2C receptors, as well as a partial SEROTONIN 5-HT1A RECEPTOR AGONIST. It is used in the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER.
Preferred term Lurasidone Hydrochloride
Entry term(s) HCl, Lurasidone
Hydrochloride, Lurasidone
Lurasidone HCl
SM 13496 - Narrower
Concept UI M0517366
Preferred term SM 13496
Entry term(s) 13496, SM
SM 13,496
SM-13,496
SM-13496
SM13,496
SM13496
Lurasidone - Broader
Concept UI M0517365
Preferred term Lurasidone
Entry term(s) N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide
Latuda - Narrower
Concept UI M000604585
Preferred term Latuda



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