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Descriptor English: Chloroquinolinols
Descriptor Spanish: Cloroquinolinoles
Descriptor cloroquinolinoles
Scope note: 8-Hidroquinolinoles clorados en los átomos de carbono 5 y-o 7. Estos compuestos son antibacterianos, antiprotozoarios y antidiarreicos, especialmente en la amebiasis, y también se han utilizado como antiseborreicos. Suelen aplicarse por vía tópica aunque también se han utilizado como aditivos de piensos para animales. Pueden causar neuropatías, en especial ópticas, y se administran frecuentemente combinados con otros agentes.
Descriptor Portuguese: Cloroquinolinóis
Descriptor French: Chloroquinoléinols
Tree number(s): D03.633.100.810.350.625.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002739
Scope note: 8-Hydroxyquinolinols chlorinated on the number 5 and/or 7 carbon atom(s). They are antibacterial, antiprotozoal, and antidiarrheal, especially in amebiasis, and have also been used as antiseborrheics. The compounds are mostly used topically, but have been used also as animal feed additives. They may cause optic and other neuropathies and are most frequently administered in combination with other agents.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Amebicides
Public MeSH Note: 91; was see under HYDROXYQUINOLINES 1975-90
Online Note: use HYDROXYQUINOLINES to search CHLOROQUINOLINOLS 1966-74 (as Prov)
History Note: 91(65); was see under HYDROXYQUINOLINES 1965-90 (Prov 1965-74)
DeCS ID: 2790
Unique ID: D002739
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/28
Chloroquinolinols - Preferred
Concept UI M0004185
Scope note 8-Hydroxyquinolinols chlorinated on the number 5 and/or 7 carbon atom(s). They are antibacterial, antiprotozoal, and antidiarrheal, especially in amebiasis, and have also been used as antiseborrheics. The compounds are mostly used topically, but have been used also as animal feed additives. They may cause optic and other neuropathies and are most frequently administered in combination with other agents.
Preferred term Chloroquinolinols



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