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Descriptor English: Antigens, Polyomavirus Transforming
Descriptor Spanish: Antígenos Transformadores de Poliomavirus
Descriptor antígenos transformadores de poliomavirus
Entry term(s) antigenos tumorales de poliomavirus
antígenos T SV40
antígenos T largos de poliomavirus
antígenos T medianos de poliomavirus
antígenos T pequeños de poliomavirus
antígenos de poliomavirus transformadores
proteínas T SV40
proteínas T de poliomavirus
proteínas del virus del sarcoma de los simios
Scope note: Antígenos de poliomavirus que causan infección y transformación celular. El antígeno T largo es necesario para la iniciación de la síntesis viral del ADN, la represión de la transcripción de la región temprana y es responsable, junto con el antígeno T mediano, de la transformación de células primarias. Los antígenos T pequeños son necesarios para completar el ciclo de infección productiva.
Descriptor Portuguese: Antígenos Transformantes de Poliomavirus
Descriptor French: Antigènes transformants de polyomavirus
Entry term(s): Antigens, Polyomavirus Tumor
Antigens, SV40 T
Polyomavirus Large T Antigens
Polyomavirus Middle T Antigens
Polyomavirus Small T Antigens
Polyomavirus T Proteins
Polyomavirus Transforming Antigens
Polyomavirus Tumor Antigens
Polyomaviruses Large T Proteins
Polyomaviruses Middle T Proteins
Polyomaviruses Small T Proteins
Proteins, Polyomavirus T
Proteins, SV40 T
SV40 T Antigens
SV40 T Proteins
Simian Sarcoma Virus Proteins
T Antigens, SV40
T Proteins, Polyomavirus
T Proteins, SV40
Transforming Antigens, Polyomavirus
Tumor Antigens, Polyomavirus
Tree number(s): D12.776.624.664.520.090
D12.776.964.350.062.090
D12.776.964.700.090
D23.050.285.062.090
D23.050.327.062.090
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000952
Scope note: Polyomavirus antigens which cause infection and cellular transformation. The large T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle T antigen for the transformation of primary cells. Small T antigen is necessary for the completion of the productive infection cycle.
Annotation: coordinate with specific polyoma virus /immunol
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Antigens, Viral (1973-1983)
Antigens, Viral, Tumor (1984-1987)
Oncogene Proteins, Viral (1986-1987)
Viral Proteins (1966-1985)
Public MeSH Note: 88
History Note: 88
Entry Version: PVTA
DeCS ID: 27952
Unique ID: D000952
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1988/01/01
Date of Entry: 1987/05/07
Revision Date: 2018/06/30
Antigens, Polyomavirus Transforming - Preferred
Concept UI M0001437
Scope note Polyomavirus antigens which cause infection and cellular transformation. The large T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle T antigen for the transformation of primary cells. Small T antigen is necessary for the completion of the productive infection cycle.
Preferred term Antigens, Polyomavirus Transforming
Entry term(s) Antigens, Polyomavirus Tumor
Polyomavirus Transforming Antigens
Polyomavirus Tumor Antigens
Transforming Antigens, Polyomavirus
Tumor Antigens, Polyomavirus
Polyomavirus T Proteins - Narrower
Concept UI M0001443
Preferred term Polyomavirus T Proteins
Entry term(s) Proteins, Polyomavirus T
T Proteins, Polyomavirus
Simian Sarcoma Virus Proteins - Narrower
Concept UI M0001441
Preferred term Simian Sarcoma Virus Proteins
Polyomavirus Middle T Antigens - Narrower
Concept UI M0001439
Preferred term Polyomavirus Middle T Antigens
Entry term(s) Polyomaviruses Middle T Proteins
Polyomavirus Small T Antigens - Narrower
Concept UI M0001440
Preferred term Polyomavirus Small T Antigens
Entry term(s) Polyomaviruses Small T Proteins
SV40 T Proteins - Narrower
Concept UI M0001442
Preferred term SV40 T Proteins
Entry term(s) Antigens, SV40 T
Proteins, SV40 T
SV40 T Antigens
T Antigens, SV40
T Proteins, SV40
Polyomavirus Large T Antigens - Narrower
Concept UI M0001438
Preferred term Polyomavirus Large T Antigens
Entry term(s) Polyomaviruses Large T Proteins



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