Descriptor in English: | Formyltetrahydrofolates |
Descriptor in Spanish: | Formiltetrahidrofolatos |
Descriptor in Portuguese: | Formiltetra-Hidrofolatos |
Descriptor in French: | Formyltétrahydrofolates |
Entry term(s): |
Formyltetrahydrofolic Acids N(10)-Formyltetrahydrofolate |
Tree number(s): |
D03.633.100.733.631.400.800.350 D08.211.840.300 |
Scope note: | Tetrahydrofolates which are substituted by a formyl group at either the nitrogen atom in the 5 position or the nitrogen atom in the 10 position. N(5)-Formyltetrahydrofolate is leucovorin (citrovorum factor) while N(10)-formyltetrahydrofolate is an active coenzyme which functions as a carrier of the formyl group in a number of enzymatic reactions. |
Annotation: | deficiency: coordinate FORMYLTETRAHYDROFOLATES /defic (IM) with FOLIC ACID DEFICIENCY (IM) |
Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
History Note: | 1991 (1976) |
DeCS UI: | 28042 |
Descriptor UI: | D005575 |
Date Established: | 1991/01/01 |
Date of Entry: | 1975/07/25 |
Revision Date: | 2018/02/27 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
|
Formyltetrahydrofolates
- Preferred
Formyltetrahydrofolic Acids
- Related but not broader or narrower
N(10)-Formyltetrahydrofolate
- Narrower
Concept UI |
M0008775 |
Scope note | Tetrahydrofolates which are substituted by a formyl group at either the nitrogen atom in the 5 position or the nitrogen atom in the 10 position. N(5)-Formyltetrahydrofolate is leucovorin (citrovorum factor) while N(10)-formyltetrahydrofolate is an active coenzyme which functions as a carrier of the formyl group in a number of enzymatic reactions. |
Preferred term | Formyltetrahydrofolates |
Concept UI |
M000638461 |
Preferred term | Formyltetrahydrofolic Acids |
Concept UI |
M0008776 |
Preferred term | N(10)-Formyltetrahydrofolate |
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