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Descriptor in English: Lipopolysaccharides
Descriptor in Spanish: Lipopolisacáridos
Descriptor in Portuguese: Lipopolissacarídeos
Descriptor in French: Lipopolysaccharides
Entry term(s): Lipoglycans
Tree number(s): D09.400.500
D09.698.718.450
D10.494
D23.050.161.616.525
D23.946.123.329.500
Scope note: Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
Annotation: oordinate with specific bacterium if pertinent
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
DeCS UI: 28155
Descriptor UI: D008070
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/06/30
Lipopolysaccharides - Preferred
Concept UI M0012577
Scope note Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
Preferred term Lipopolysaccharides
Entry term(s) Lipoglycans



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