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Descriptor English: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine
Descriptor Spanish: 4,5-dihidro-1-(3-(trifluorometil)fenil)-1H-pirazol-3-amina
Descriptor 4,5-dihidro-1-(3-(trifluorometil)fenil)-1H-pirazol-3-amina
Scope note: Inhibidor doble tanto de la ciclooxigenasa como de la lipoxigenasa. Ejerce un efecto antiinflamatorio merced a la inhibición de la formación de prostaglandinas y leucotrienos. Esta sustancia también potencia la vasoconstricción hipóxica pulmonar y tiene un efecto protector de la isquemia miocárdica.
Descriptor Portuguese: 4,5-Di-Hidro-1-(3-(Trifluormetil)Fenil)-1H-Pirazol-3-Amina
Descriptor French: 1-(3-(Trifluorométhyl)phényl)-4,5-dihydro-1H-pyrazol-3-amine
Entry term(s): BW 755C
BW-755C
BW755C
Tree number(s): D03.383.129.539.180
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015772
Scope note: A dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Inflammatory Agents, Non-Steroidal
Antiinflamatorios no Esteroideos
Anti-Inflamatórios não Esteroides
Anti-inflammatoires non stéroïdiens
antiinflamatorios no esteroideos
Lipoxygenase Inhibitors
Inhibidores de la Lipooxigenasa
Inibidores de Lipoxigenase
Inhibiteurs de la lipoxygénase
inhibidores de la lipooxigenasa
Cyclooxygenase Inhibitors
Inhibidores de la Ciclooxigenasa
Inibidores de Ciclo-Oxigenase
Inhibiteurs des cyclooxygénases
inhibidores de ciclooxigenasas
Registry Number: 66000-40-6
CAS Type 1 Name: 1H-Pyrazol-3-amine, 4,5-dihydro-1-(3-(trifluoromethyl)phenyl)-
Previous Indexing: Anti-Inflammatory Agents (1966-1986)
Anti-Inflammatory Agents, Non-Steroidal (1987-1989)
Pyrazoles (1966-1989)
Public MeSH Note: 2005; see BW-775C 1996-2004; see BW 755C 1990; see BW-755C 1990-1995
History Note: 2005(1991)
DeCS ID: 29238
Unique ID: D015772
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2018/06/30
4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine - Preferred
Concept UI M0373905
Scope note A dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia.
Preferred term 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine
BW-755C - Narrower
Concept UI M0024166
Preferred term BW-755C
Entry term(s) BW 755C
BW755C



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