Descriptor English: | 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine | ||||
Descriptor Spanish: |
4,5-dihidro-1-(3-(trifluorometil)fenil)-1H-pirazol-3-amina
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Descriptor Portuguese: | 4,5-Di-Hidro-1-(3-(Trifluormetil)Fenil)-1H-Pirazol-3-Amina | ||||
Descriptor French: | 1-(3-(Trifluorométhyl)phényl)-4,5-dihydro-1H-pyrazol-3-amine | ||||
Entry term(s): |
BW 755C BW-755C BW755C |
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Tree number(s): |
D03.383.129.539.180 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015772 | ||||
Scope note: | A dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia. |
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Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Pharm Action: |
Anti-Inflammatory Agents, Non-Steroidal Antiinflamatorios no Esteroideos Anti-Inflamatórios não Esteroides Anti-inflammatoires non stéroïdiens antiinflamatorios no esteroideos Lipoxygenase Inhibitors Inhibidores de la Lipooxigenasa Inibidores de Lipoxigenase Inhibiteurs de la lipoxygénase inhibidores de la lipooxigenasa Cyclooxygenase Inhibitors Inhibidores de la Ciclooxigenasa Inibidores de Ciclo-Oxigenase Inhibiteurs des cyclooxygénases inhibidores de ciclooxigenasas |
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Registry Number: | 66000-40-6 | ||||
CAS Type 1 Name: | 1H-Pyrazol-3-amine, 4,5-dihydro-1-(3-(trifluoromethyl)phenyl)- | ||||
Previous Indexing: |
Anti-Inflammatory Agents (1966-1986) Anti-Inflammatory Agents, Non-Steroidal (1987-1989) Pyrazoles (1966-1989) |
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Public MeSH Note: | 2005; see BW-775C 1996-2004; see BW 755C 1990; see BW-755C 1990-1995 |
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History Note: | 2005(1991) |
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DeCS ID: | 29238 | ||||
Unique ID: | D015772 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 1990/01/01 | ||||
Date of Entry: | 1989/05/25 | ||||
Revision Date: | 2018/06/30 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine
- Preferred
BW-755C
- Narrower
Concept UI |
M0373905 |
Scope note | A dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia. |
Preferred term | 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine |
Concept UI |
M0024166 |
Preferred term | BW-755C |
Entry term(s) |
BW 755C BW755C |
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