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Descriptor in English: Rimonabant
Descriptor in Spanish: Rimonabant
Descriptor in Portuguese: Rimonabanto
Descriptor in French: Rimonabant
Entry term(s): Acomplia
N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride
Rimonabant Hydrochloride
SR 141716
SR 141716A
SR-141716A
SR141716
SR141716A
Zimulti
Tree number(s): D03.383.129.539.888
D03.383.621.834
Scope note: A pyrazole and piperidine derivative that acts as a selective cannabinoid type-1 receptor (CB1 RECEPTOR) antagonist. It inhibits the proliferation and maturation of ADIPOCYTES, improves lipid and glucose metabolism, and regulates food intake and energy balance. It is used in the management of OBESITY.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 2019 (1994)
DeCS UI: 57586
Descriptor UI: D000077285
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/27
Rimonabant - Preferred
Concept UI M0235470
Scope note A pyrazole and piperidine derivative that acts as a selective cannabinoid type-1 receptor (CB1 RECEPTOR) antagonist. It inhibits the proliferation and maturation of ADIPOCYTES, improves lipid and glucose metabolism, and regulates food intake and energy balance. It is used in the management of OBESITY.
Preferred term Rimonabant
SR141716 - Narrower
Concept UI M0445880
Preferred term SR141716
Entry term(s) SR 141716
Rimonabant Hydrochloride - Narrower
Concept UI M000640319
Preferred term Rimonabant Hydrochloride
Entry term(s) N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride
Zimulti - Narrower
Concept UI M000640318
Preferred term Zimulti
SR 141716A - Narrower
Concept UI M0235474
Preferred term SR 141716A
Entry term(s) SR-141716A
SR141716A
Acomplia - Narrower
Concept UI M0514542
Preferred term Acomplia



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