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Descriptor English: Rimonabant
Descriptor Spanish: Rimonabant
Descriptor rimonabant
Entry term(s) SR 141716
SR 141716A
SR-141716A
SR141716
SR141716A
acomplia
hidrocloruro de N-(piperidin-1-il)-5-(4-clorofenil)-1-(2,4-diclorofenil)-4-metil-1H-pirazol-3-carboxamida
hidrocloruro de rimonabant
zimulti
Scope note: Derivado pirazólico y piperidínico que actúa como antagonista selectivo de los receptores de cannabinoides de tipo 1 (RECEPTOR CB1). Inhibe la proliferación y la maduración de los ADIPOCITOS, mejora el metabolismo de los lípidos y de la glucosa y regula la ingesta alimentaria y el balance energético. Se usa en el tratamiento de la OBESIDAD.
Descriptor Portuguese: Rimonabanto
Descriptor French: Rimonabant
Entry term(s): Acomplia
N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride
Rimonabant Hydrochloride
SR 141716
SR 141716A
SR-141716A
SR141716
SR141716A
Zimulti
Tree number(s): D03.383.129.539.888
D03.383.621.834
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077285
Scope note: A pyrazole and piperidine derivative that acts as a selective cannabinoid type-1 receptor (CB1 RECEPTOR) antagonist. It inhibits the proliferation and maturation of ADIPOCYTES, improves lipid and glucose metabolism, and regulates food intake and energy balance. It is used in the management of OBESITY.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Obesity Agents
Cannabinoid Receptor Antagonists
Registry Number: RML78EN3XE
CAS Type 1 Name: 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-
Public MeSH Note: 2019; RIMONABANT was indexed under PYRAZOLES and PIPERIDINES 1994-2018
History Note: 2019 (1994)
DeCS ID: 57586
Unique ID: D000077285
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/27
Rimonabant - Preferred
Concept UI M0235470
Scope note A pyrazole and piperidine derivative that acts as a selective cannabinoid type-1 receptor (CB1 RECEPTOR) antagonist. It inhibits the proliferation and maturation of ADIPOCYTES, improves lipid and glucose metabolism, and regulates food intake and energy balance. It is used in the management of OBESITY.
Preferred term Rimonabant
SR141716 - Narrower
Concept UI M0445880
Preferred term SR141716
Entry term(s) SR 141716
Rimonabant Hydrochloride - Narrower
Concept UI M000640319
Preferred term Rimonabant Hydrochloride
Entry term(s) N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride
Zimulti - Narrower
Concept UI M000640318
Preferred term Zimulti
SR 141716A - Narrower
Concept UI M0235474
Preferred term SR 141716A
Entry term(s) SR-141716A
SR141716A
Acomplia - Narrower
Concept UI M0514542
Preferred term Acomplia



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