Descriptor English: | 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine | ||||
Descriptor Spanish: |
4,5-dihidro-1-(3-(trifluorometil)fenil)-1H-pirazol-3-amina
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Descriptor Portuguese: | 4,5-Di-Hidro-1-(3-(Trifluormetil)Fenil)-1H-Pirazol-3-Amina | ||||
Descriptor French: | 1-(3-(Trifluorométhyl)phényl)-4,5-dihydro-1H-pyrazol-3-amine | ||||
Entry term(s): |
BW 755C BW-755C BW755C |
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Tree number(s): |
D03.383.129.539.180 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015772 | ||||
Scope note: | A dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia. |
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Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Pharm Action: |
Anti-Inflammatory Agents, Non-Steroidal Lipoxygenase Inhibitors Cyclooxygenase Inhibitors |
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Registry Number: | 66000-40-6 | ||||
CAS Type 1 Name: | 1H-Pyrazol-3-amine, 4,5-dihydro-1-(3-(trifluoromethyl)phenyl)- | ||||
Previous Indexing: |
Anti-Inflammatory Agents (1966-1986) Anti-Inflammatory Agents, Non-Steroidal (1987-1989) Pyrazoles (1966-1989) |
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Public MeSH Note: | 2005; see BW-775C 1996-2004; see BW 755C 1990; see BW-755C 1990-1995 |
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History Note: | 2005(1991) |
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DeCS ID: | 29238 | ||||
Unique ID: | D015772 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 1990/01/01 | ||||
Date of Entry: | 1989/05/25 | ||||
Revision Date: | 2018/06/30 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine
- Preferred
BW-755C
- Narrower
Concept UI |
M0373905 |
Scope note | A dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia. |
Preferred term | 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine |
Concept UI |
M0024166 |
Preferred term | BW-755C |
Entry term(s) |
BW 755C BW755C |
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