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Descriptor English: Growth Hormone-Releasing Hormone
Descriptor Spanish: Hormona Liberadora de Hormona del Crecimiento
Descriptor hormona liberadora de hormona del crecimiento
Entry term(s) factor 44 liberador de somatotropina
factor liberador de hormona del crecimiento
hormona liberadora de somatotropina
somatocrinina
Scope note: Péptido de 44 aminoácidos en la mayoría de las especies que estimula la liberación y la síntesis de HORMONA DEL CRECIMIENTO. La GHRF (o GRF) es sintetizada por las neuronas del NÚCLEO ARQUEADO del HIPOTÁLAMO. Después de ser liberada en la circulación portal hipofisaria, la GHRF estimula la liberación de GH por las células somatotróficas (SOMATOTROFOS) de la HIPÓFISIS.
Descriptor Portuguese: Hormônio Liberador de Hormônio do Crescimento
Descriptor French: Hormone de libération de l'hormone de croissance
Entry term(s): GHRH 1-44
GRF 1-44
Growth Hormone Releasing Factor
Growth Hormone Releasing Factor 44
Growth Hormone Releasing Hormone
Growth Hormone-Releasing Factor
Growth Hormone-Releasing Factor 44
Human Pancreatic Growth Hormone-Releasing Factor
Somatocrinin
Somatoliberin
Somatotropin Releasing Factor 44
Somatotropin Releasing Hormone
Somatotropin-Releasing Factor 44
Somatotropin-Releasing Hormone
hpGRF 44
Tree number(s): D06.472.699.327.740.860
D12.644.400.400.740.860
D12.644.548.365.740.860
D12.776.631.650.405.740.860
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013007
Scope note: A peptide of 44 amino acids in most species that stimulates the release and synthesis of GROWTH HORMONE. GHRF (or GRF) is synthesized by neurons in the ARCUATE NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, GHRF stimulates GH release by the SOMATOTROPHS in the PITUITARY GLAND.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Hormones
Registry Number: 9034-39-3
CAS Type 1 Name: Somatoliberin
Public MeSH Note: 2007; see SOMATOTROPIN-RELEASING HORMONE 1991-2006, see SOMATOTROPIN RELEASING HORMONE 1974-1990
History Note: 2007 (1974)
DeCS ID: 29298
Unique ID: D013007
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/11/23
Growth Hormone-Releasing Hormone - Preferred
Concept UI M0020158
Scope note A peptide of 44 amino acids in most species that stimulates the release and synthesis of GROWTH HORMONE. GHRF (or GRF) is synthesized by neurons in the ARCUATE NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, GHRF stimulates GH release by the SOMATOTROPHS in the PITUITARY GLAND.
Preferred term Growth Hormone-Releasing Hormone
Entry term(s) GHRH 1-44
GRF 1-44
Growth Hormone Releasing Factor
Growth Hormone Releasing Factor 44
Growth Hormone Releasing Hormone
Growth Hormone-Releasing Factor
Growth Hormone-Releasing Factor 44
Somatocrinin
Somatoliberin
Somatotropin Releasing Factor 44
Somatotropin Releasing Hormone
Somatotropin-Releasing Factor 44
Somatotropin-Releasing Hormone
Human Pancreatic Growth Hormone-Releasing Factor - Narrower
Concept UI M0482278
Scope note Ectopic GHRH secreted by human pancreatic tumor.
Preferred term Human Pancreatic Growth Hormone-Releasing Factor
Entry term(s) hpGRF 44



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