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Descriptor English: Carbazilquinone
Descriptor Spanish: Carbazilquinona
Descriptor carbacilquinona
Entry term(s) carbocuona
carboquinona
Scope note: Agente alquilante estructuralmente similar a la MITOMICINA. Es efectiva en el tratamiento de la leucemia y otras diversas neoplasias en ratones. Causa leucemia y trombocitopenia en casi todos los pacientes humanos.
Descriptor Portuguese: Carbazilquinona
Descriptor French: Carboquone
Entry term(s): Carboquinone
Carboquone
Esquinon
Tree number(s): D02.806.250.180
D03.383.097.217.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002225
Scope note: An alkylating agent structurally similar to MITOMYCIN and found to be effective in the treatment of leukemia and various other neoplasms in mice. It causes leukemia and thrombocytopenia in almost all human patients.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents, Alkylating
Registry Number: 1CB0HBT12C
CAS Type 1 Name: 2,5-Cyclohexadiene-1,4-dione, 2-(2-((aminocarbonyl)oxy)-1-methoxyethyl)-3,6-bis(1-aziridinyl)-5-methyl-
Previous Indexing: Azirines (1971-1974)
Carbamates (1972-1974)
Quinones (1972-1974)
Public MeSH Note: 91; was see under AZIRINES 1975-90
History Note: 91(75); was see under AZIRINES 1975-90
DeCS ID: 29593
Unique ID: D002225
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/27
Carbazilquinone - Preferred
Concept UI M0003336
Scope note An alkylating agent structurally similar to MITOMYCIN and found to be effective in the treatment of leukemia and various other neoplasms in mice. It causes leukemia and thrombocytopenia in almost all human patients.
Preferred term Carbazilquinone
Entry term(s) Carboquinone
Carboquone
Esquinon - Narrower
Concept UI M0352338
Preferred term Esquinon



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