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Descriptor English: 3T3 Cells
Descriptor Spanish: Células 3T3
Descriptor células 3T3
Scope note: Línea celular derivada de los fibroblastos de embriones desagregados de ratones suizos. Ésta línea es un sistema hospedador in vitro de gran valor para los estudios de transformación de virus oncogénicos, ya que las células 3T3 poseen una elevada sensibilidad a la inhibición por contacto.
Descriptor Portuguese: Células 3T3
Descriptor French: Cellules 3T3
Entry term(s): 3T3 Cell
Cell, 3T3
Cells, 3T3
Tree number(s): A11.251.210.100
A11.329.228.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016475
Scope note: Cell lines whose original growing procedure consisted being transferred (T) every 3 days and plated at 300,000 cells per plate (J Cell Biol 17:299-313, 1963). Lines have been developed using several different strains of mice. Tissues are usually fibroblasts derived from mouse embryos but other types and sources have been developed as well. The 3T3 lines are valuable in vitro host systems for oncogenic virus transformation studies, since 3T3 cells possess a high sensitivity to CONTACT INHIBITION.
Annotation: almost always NIM with no subheadings; check ANIMALS & MICE; do not routinely add FIBROBLASTS or EMBRYO, MAMMALIAN
Allowable Qualifiers: CH chemistry
CL classification
CY cytology
DE drug effects
EN enzymology
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Previous Indexing: Cell Line (1966-1991)
Public MeSH Note: 1992
History Note: 1992
DeCS ID: 29738
Unique ID: D016475
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/01/03
Revision Date: 2013/07/08
3T3 Cells - Preferred
Concept UI M0025161
Scope note Cell lines whose original growing procedure consisted being transferred (T) every 3 days and plated at 300,000 cells per plate (J Cell Biol 17:299-313, 1963). Lines have been developed using several different strains of mice. Tissues are usually fibroblasts derived from mouse embryos but other types and sources have been developed as well. The 3T3 lines are valuable in vitro host systems for oncogenic virus transformation studies, since 3T3 cells possess a high sensitivity to CONTACT INHIBITION.
Preferred term 3T3 Cells
Entry term(s) 3T3 Cell
Cell, 3T3
Cells, 3T3



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