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Descriptor in English: Radioimmunotherapy
Descriptor in Spanish: Radioinmunoterapia
Descriptor in Portuguese: Radioimunoterapia
Descriptor in French: Radioimmunothérapie
Entry term(s): Immunoradiotherapies
Immunoradiotherapy
Radioimmunotherapies
Tree number(s): E02.095.465.425.750
E02.186.750
E02.815.520
Scope note: Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).
Annotation: coordinate with disease /radiother
Allowable Qualifiers: AE adverse effects
CL classification
EC economics
ES ethics
HI history
IS instrumentation
MO mortality
MT methods
NU nursing
PX psychology
SN statistics & numerical data
ST standards
TD trends
VE veterinary
History Note: 92
DeCS UI: 29854
Descriptor UI: D016499
Date Established: 1992/01/01
Date of Entry: 1991/05/02
Revision Date: 2009/07/06
Radioimmunotherapy - Preferred
Concept UI M0025194
Scope note Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).
Preferred term Radioimmunotherapy
Entry term(s) Immunoradiotherapies
Immunoradiotherapy
Radioimmunotherapies



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