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Descriptor English: Radioimmunotherapy
Descriptor Spanish: Radioinmunoterapia
Descriptor radioinmunoterapia
Scope note: Radioterapia en la que radionúclidos citotóxicos se enlazan a anticuerpos con el fin de liberar toxinas directamente en los tumores diana. El tratamiento con radiación dirigida es mejor que el tratamiento con toxinas conjugadas a anticuerpos (INMUNOTOXINAS) pues tiene la ventaja de que las células adyacentes al tumor, que no tienen los determinantes antigénicos apropiados, pueden ser destruidas por radiación cruzada. En ocasiones, la radioinmunoterapia recibe la denominación de radioterapia dirigida, pero este último término puede referirse también a radionúclidos unidos a moléculas no inmunitarias (ver RADIOTERAPIA).
Descriptor Portuguese: Radioimunoterapia
Descriptor French: Radioimmunothérapie
Entry term(s): Immunoradiotherapies
Immunoradiotherapy
Radioimmunotherapies
Tree number(s): E02.095.465.425.750
E02.186.750
E02.815.520
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016499
Scope note: Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).
Annotation: coordinate with disease /radiother
Allowable Qualifiers: AE adverse effects
CL classification
EC economics
ES ethics
HI history
IS instrumentation
MO mortality
MT methods
NU nursing
PX psychology
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Previous Indexing: Antibodies, Monoclonal/therapeutic use (1984-1991)
Immunotherapy (1984-1991)
specific radioisotope/therapeutic use (1981-1991)
Public MeSH Note: 92
History Note: 92
Entry Version: RADIOIMMUNOTHER
DeCS ID: 29854
Unique ID: D016499
NLM Classification: QZ 270
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/05/02
Revision Date: 2009/07/06
Radioimmunotherapy - Preferred
Concept UI M0025194
Scope note Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).
Preferred term Radioimmunotherapy
Entry term(s) Immunoradiotherapies
Immunoradiotherapy
Radioimmunotherapies



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