Descriptor English: | Mitomycin | ||||||
Descriptor Spanish: |
Mitomicina
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Descriptor Portuguese: | Mitomicina | ||||||
Descriptor French: | Mitomycine | ||||||
Entry term(s): |
Ametycine Mitocin C Mitocin-C MitocinC Mitomycin C Mitomycin-C Mutamycin NSC 26980 NSC-26980 NSC26980 |
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Tree number(s): |
D02.806.400.249.350 D03.383.097.500.350 D03.633.100.473.412.249.350 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D016685 | ||||||
Scope note: | An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis. |
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Annotation: | MITOMYCINS is also available |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Entry Combination: |
analogs & derivatives:Mitomycins
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Pharm Action: |
Alkylating Agents Antibiotics, Antineoplastic Cross-Linking Reagents Nucleic Acid Synthesis Inhibitors |
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Registry Number: | 50SG953SK6 | ||||||
CAS Type 1 Name: | Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))- | ||||||
Previous Indexing: |
Mitomycins (1966-1991) |
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Public MeSH Note: | 2000(1992); see MITOMYCIN C 1992-1999; MITOMYCIN C was indexed under MITOMYCINS 1981-1990 |
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History Note: | 2000(1992); for MITOMYCIN use MITOMYCIN (NM) 1981-1991 |
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DeCS ID: | 29961 | ||||||
Unique ID: | D016685 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1992/01/01 | ||||||
Date of Entry: | 1991/01/25 | ||||||
Revision Date: | 2016/05/31 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Mitomycin
- Preferred
Mitocin-C
- Narrower
NSC-26980
- Narrower
Ametycine
- Narrower
Mutamycin
- Narrower
Concept UI |
M0013948 |
Scope note | An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis. |
Preferred term | Mitomycin |
Entry term(s) |
Mitomycin C Mitomycin-C |
Concept UI |
M0353143 |
Preferred term | Mitocin-C |
Entry term(s) |
Mitocin C MitocinC |
Concept UI |
M0353141 |
Preferred term | NSC-26980 |
Entry term(s) |
NSC 26980 NSC26980 |
Concept UI |
M0353144 |
Preferred term | Ametycine |
Concept UI |
M0353142 |
Preferred term | Mutamycin |
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