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Descriptor English: Lewy Bodies
Descriptor Spanish: Cuerpos de Lewy
Descriptor cuerpos de Lewy
Entry term(s) corpúsculos de Lewy
neurita de Lewy
neuritas de Lewy
Scope note: Inclusiones intracitoplasmáticas, eosinofílicas, de redondas a alargadas, que se encuentran en las vacuolas de las neuronas dañadas o fragmentadas. La presencia de los cuerpos de Lewy resulta el marcador histológico de los cambios degenerativos en la ENFERMEDAD CON CUERPOS DE LEWY y en la ENFERMEDAD DE PARKINSON, pero también se pueden observar en otras condiciones neurológicas. Se encuentran típicamente en la sustancia negra y el locus coeruleus pero también se observan en la base del cerebro anterior, en los núcleos hipotalámicos y en la neocorteza.
Descriptor Portuguese: Corpos de Lewy
Descriptor French: Corps de Lewy
Entry term(s): Lewy Body
Lewy Neurite
Lewy Neurites
Neurite, Lewy
Tree number(s): A11.284.420.460
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016631
Scope note: Intracytoplasmic, eosinophilic, round to elongated inclusions found in vacuoles of injured or fragmented neurons. The presence of Lewy bodies is the histological marker of the degenerative changes in LEWY BODY DISEASE and PARKINSON DISEASE but they may be seen in other neurological conditions. They are typically found in the substantia nigra and locus coeruleus but they are also seen in the basal forebrain, hypothalamic nuclei, and neocortex.
Annotation: LEWY BODY DISEASE is also available
Allowable Qualifiers: CH chemistry
CL classification
DE drug effects
EN enzymology
GE genetics
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Previous Indexing: Cellular Inclusions (1972-1991)
Cytoplasmic Granules (1966-1991)
Public MeSH Note: 92
History Note: 92
Related: Lewy Body Disease MeSH
Parkinson Disease MeSH
Synucleinopathies MeSH
DeCS ID: 30008
Unique ID: D016631
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/01/25
Revision Date: 2020/05/27
Lewy Bodies - Preferred
Concept UI M0025347
Scope note Intracytoplasmic, eosinophilic, round to elongated inclusions found in vacuoles of injured or fragmented neurons. The presence of Lewy bodies is the histological marker of the degenerative changes in LEWY BODY DISEASE and PARKINSON DISEASE but they may be seen in other neurological conditions. They are typically found in the substantia nigra and locus coeruleus but they are also seen in the basal forebrain, hypothalamic nuclei, and neocortex.
Preferred term Lewy Bodies
Entry term(s) Lewy Body
Lewy Neurites - Related but not broader or narrower
Concept UI M000648560
Preferred term Lewy Neurites
Entry term(s) Lewy Neurite
Neurite, Lewy



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