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Descriptor English: Fleroxacin
Descriptor Spanish: Fleroxacino
Descriptor fleroxacina
Entry term(s) fleroxacino
Scope note: Fluoroquinolona de amplio espectro antimicrobiano. Este fármaco inhibe la actividad super-enrrolladora del ADN de la GIRASA DEL ADN.
Descriptor Portuguese: Fleroxacino
Descriptor French: Fléroxacine
Entry term(s): AM 833
AM-833
AM833
Quinodis
Ro 23 6240
Ro 23-6240
Ro 236240
Tree number(s): D03.633.100.810.835.322.186.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016576
Scope note: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Infective Agents
Topoisomerase II Inhibitors
Registry Number: N804LDH51K
CAS Type 1 Name: 3-Quinolinecarboxylic acid, 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-
Previous Indexing: Anti-Infective Agents (1966-1988)
Anti-Infective Agents, Quinolone (1989-1991)
Ciprofloxacin/analogs & derivatives (1987-1991)
Quinolines (1966-1986)
Public MeSH Note: 92; FLEROXACIN was indexed under QUINOLINES 1986 & under CIPROFLOXACIN/analogs & derivatives 1987-91
Online Note: use FLEROXACIN (NM) to search FLEROXACIN 1986-91
History Note: 92; was FLEROXACIN (NM) 1986-91
DeCS ID: 30102
Unique ID: D016576
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/01/02
Revision Date: 2017/05/24
Fleroxacin - Preferred
Concept UI M0025289
Scope note A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
Preferred term Fleroxacin
Quinodis - Narrower
Concept UI M0478259
Preferred term Quinodis
Ro 23-6240 - Narrower
Concept UI M0353990
Preferred term Ro 23-6240
Entry term(s) Ro 23 6240
Ro 236240
AM-833 - Narrower
Concept UI M0353991
Preferred term AM-833
Entry term(s) AM 833
AM833



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