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Descriptor in English: Bone Remodeling
Descriptor in Spanish: Remodelación Ósea
Descriptor in Portuguese: Remodelação Óssea
Descriptor in French: Remodelage osseux
Entry term(s): Bone Turnover
Bone Turnovers
Remodeling, Bone
Turnover, Bone
Turnovers, Bone
Tree number(s): G11.427.213
G16.762.150
Scope note: The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
Annotation: note category: an aspect of bone physiol
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
History Note: 92
DeCS UI: 30227
Descriptor UI: D016723
Date Established: 1992/01/01
Date of Entry: 1991/04/29
Revision Date: 2016/06/02
Bone Remodeling - Preferred
Concept UI M0025466
Scope note The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
Preferred term Bone Remodeling
Entry term(s) Bone Turnover
Bone Turnovers
Remodeling, Bone
Turnover, Bone
Turnovers, Bone



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