Descriptor English: | Alternative Splicing | ||||||
Descriptor Spanish: |
Empalme Alternativo
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Descriptor Portuguese: | Processamento Alternativo | ||||||
Descriptor French: | Épissage alternatif | ||||||
Entry term(s): |
Alternate Splicing Alternate Splicings Alternative RNA Splicing Alternative RNA Splicings Alternative Splicings Nested Transcript Nested Transcripts RNA Splicing, Alternative RNA Splicings, Alternative Splicing, Alternate Splicing, Alternative Splicing, Alternative RNA Splicings, Alternate Splicings, Alternative Splicings, Alternative RNA Transcript, Nested Transcripts, Nested |
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Tree number(s): |
G02.111.760.700.100 G03.839.700.100 G05.308.700.700.100 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D017398 | ||||||
Scope note: | A process whereby multiple RNA transcripts are generated from a single gene. Alternative splicing involves the splicing together of other possible sets of EXONS during the processing of some, but not all, transcripts of the gene. Thus a particular exon may be connected to any one of several alternative exons to form a mature RNA. The alternative forms of mature MESSENGER RNA produce PROTEIN ISOFORMS in which one part of the isoforms is common while the other parts are different. |
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Annotation: | for NESTED TRANSCRIPTS also index the RNA; do not confuse with NESTED GENES; for nested primers use NESTED PCR; (POLYMERASE CHAIN REACTION) |
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Allowable Qualifiers: |
DE drug effects ES ethics GE genetics IM immunology PH physiology RE radiation effects |
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Previous Indexing: |
RNA Splicing (1982-1992) |
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Public MeSH Note: | 93 |
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History Note: | 93 |
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Related: |
Nested Genes
MeSH Protein Isoforms MeSH RNA Splice Sites MeSH | ||||||
DeCS ID: | 30858 | ||||||
Unique ID: | D017398 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1993/01/01 | ||||||
Date of Entry: | 1992/05/13 | ||||||
Revision Date: | 2016/05/02 |
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PHENOMENA AND PROCESSES
Chemical Phenomena [G02]Chemical Phenomena -
PHENOMENA AND PROCESSES
Metabolism [G03]Metabolism -
PHENOMENA AND PROCESSES
Genetic Phenomena [G05]Genetic Phenomena
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Alternative Splicing
- Preferred
Nested Transcripts
- Related but not broader or narrower
Concept UI |
M0026412 |
Scope note | A process whereby multiple RNA transcripts are generated from a single gene. Alternative splicing involves the splicing together of other possible sets of EXONS during the processing of some, but not all, transcripts of the gene. Thus a particular exon may be connected to any one of several alternative exons to form a mature RNA. The alternative forms of mature MESSENGER RNA produce PROTEIN ISOFORMS in which one part of the isoforms is common while the other parts are different. |
Preferred term | Alternative Splicing |
Entry term(s) |
Alternate Splicing Alternate Splicings Alternative RNA Splicing Alternative RNA Splicings Alternative Splicings RNA Splicing, Alternative RNA Splicings, Alternative Splicing, Alternate Splicing, Alternative Splicing, Alternative RNA Splicings, Alternate Splicings, Alternative Splicings, Alternative RNA |
Concept UI |
M0411969 |
Scope note | Alternatively spliced RNA transcripts that are derived from a set of exons that are located in the middle of the primary transcript (RNA PRECURSORS), between unused exons. |
Preferred term | Nested Transcripts |
Entry term(s) |
Nested Transcript Transcript, Nested Transcripts, Nested |
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