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Descriptor English: Zinostatin
Descriptor Spanish: Cinostatina
Descriptor cinostatina
Entry term(s) neocarcinostatina
Scope note: Enedina que alquila el ADN y el ARN al igjual que la MITOMICINA, de modo que es citotóxico.
Descriptor Portuguese: Zinostatina
Descriptor French: Zinostatine
Entry term(s): Neocarzinostatin
Tree number(s): D02.455.326.271.244.500
D02.455.326.397.680.500.500.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009353
Scope note: An enediyne that alkylates DNA and RNA like MITOMYCIN does, so it is cytotoxic.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Cytotoxins
Nucleic Acid Synthesis Inhibitors
Registry Number: 9014-02-2
Previous Indexing: Antibiotics, Antineoplastic (1971-1974)
Bacterial Proteins (1974)
Public MeSH Note: 93; was NEOCARZINOSTATIN 1975-92 (see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90)
Online Note: use ZINOSTATIN to search NEOCARZINOSTATIN 1975-92
History Note: 93; was NEOCARZINOSTATIN 1975-92 (see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90)
DeCS ID: 30876
Unique ID: D009353
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2018/07/05
Zinostatin - Preferred
Concept UI M0014562
Scope note An enediyne that alkylates DNA and RNA like MITOMYCIN does, so it is cytotoxic.
Preferred term Zinostatin
Entry term(s) Neocarzinostatin



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