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Descriptor English: Vaccines, Conjugate
Descriptor Spanish: Vacunas Conjugadas
Descriptor vacunas conjugadas
Entry term(s) vacuna conjugada
Scope note: Vacunas semisintéticas constituidas por polisacáridos que son antígenos de microorganismos unidos a moléculas proteicas transportadoras. La proteína transportadora es reconocida por los macrófagos y linfocitos T, aumentando así la inmunidad. Las vacunas conjugadas inducen la formación de anticuerpos en personas que no responden al polisacárido solo, inducen niveles más elevados de anticuerpos y muestran una respuesta de refuerzo al repetir la inyección.
Descriptor Portuguese: Vacinas Conjugadas
Descriptor French: Vaccins conjugués
Entry term(s): Conjugate Vaccine
Conjugate Vaccines
Vaccine, Conjugate
Tree number(s): D20.215.894.865.900
D23.050.865.900
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018074
Scope note: Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.
Annotation: "induce antibody formation in people not responsive to polysaccharide alone"; semisynthetic vaccines; coord NIM with specific vaccine (IM)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
MI microbiology
PD pharmacology
PO poisoning
RE radiation effects
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
VI virology
Previous Indexing: Vaccines, Synthetic (1988-1993)
vaccine components/immunology (1984-1993)
Public MeSH Note: 94
History Note: 94
DeCS ID: 30984
Unique ID: D018074
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/06/04
Revision Date: 2020/05/27
Vaccines, Conjugate - Preferred
Concept UI M0027265
Scope note Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.
Preferred term Vaccines, Conjugate
Entry term(s) Conjugate Vaccine
Conjugate Vaccines
Vaccine, Conjugate



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