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Descriptor English: Signal Recognition Particle
Descriptor Spanish: Partícula de Reconocimiento de Señal
Descriptor partícula de reconocimiento de señal
Entry term(s) SRP
SRP (Partícula de Reconocimiento de Señal)
Scope note: Complejo de ribonucleoproteína del citosol que actúa induciendo la detención de la elongación de las proteínas presecretoras y de membrana hasta que los ribosomas se asocian con el retículo endoplasmático rugoso. Está constituido por ARN 7S y por al menos seis subunidades polipeptídicas (peso molecular relativo 9, 14, 19, 54, 68, y 72K).
Descriptor Portuguese: Partícula de Reconhecimento de Sinal
Descriptor French: Particule de reconnaissance du signal
Entry term(s): Particle, Signal Recognition
Recognition Particle, Signal
SRP (Signal Recognition Particle)
Tree number(s): D12.776.157.725.500.750.800
D12.776.664.962.500.750.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018271
Scope note: A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory and membrane proteins until the ribosome becomes associated with the rough endoplasmic reticulum. It consists of a 7S RNA and at least six polypeptide subunits (relative molecular masses 9, 14, 19, 54, 68, and 72K).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Ribonucleoproteins (1985-1993)
Public MeSH Note: 94; SIGNAL RECOGNITION PARTICLE was indexed under RIBONUCLEOPROTEINS 1985-93
Online Note: use SIGNAL RECOGNITION PARTICLE (NM) to search SIGNAL RECOGNITION PARTICLE 1985-93
History Note: 94; was SIGNAL RECOGNITION PARTICLE (NM) 1985-93
Entry Version: SIG REC PART
Related: Protein Sorting Signals MeSH
DeCS ID: 31046
Unique ID: D018271
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/06/03
Revision Date: 2005/06/30
Signal Recognition Particle - Preferred
Concept UI M0027499
Scope note A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory and membrane proteins until the ribosome becomes associated with the rough endoplasmic reticulum. It consists of a 7S RNA and at least six polypeptide subunits (relative molecular masses 9, 14, 19, 54, 68, and 72K).
Preferred term Signal Recognition Particle
Entry term(s) Particle, Signal Recognition
Recognition Particle, Signal
SRP (Signal Recognition Particle)



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