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Descriptor English: Leukotriene C4
Descriptor Spanish: Leucotrieno C4
Descriptor leucotrieno C4
Entry term(s) LTC4
Scope note: Producto de la conjugación del LEUCOTRIENO A4 y el glutation. Es el principal metabolito del ácido araquidónico en los macrófagos y mastocitos humanos, así como en el tejido pulmonar sensibilizado por antígenos. Estimula la secreción mucosa del pulmón y produce contracción del músculo liso no vascular y de algún MÚSCULO LISO VASCULAR. (Dictionary of Prostaglandins and Related Compounds, 1990)
Descriptor Portuguese: Leucotrieno C4
Descriptor French: Leucotriène C4
Entry term(s): LTC4
Leukotriene C
Leukotriene C 1
Leukotriene C 4
Leukotriene C-1
Leukotriene C-4
Leukotriene C1
Leukotrienes C
Tree number(s): D10.251.355.255.100.450.855.455
D10.251.355.310.166.887.855.455
D23.469.050.175.450.725.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017997
Scope note: The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 2CU6TT9V48
CAS Type 1 Name: Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))-
Previous Indexing: SRS-A (1981-1993)
Public MeSH Note: 94; was see SRS-A 1983-93; LEUKOTRIENE C1 & LEUKOTRIENES C were see SRS-A 1983-93
Online Note: use SRS-A to search LEUKOTRIENE C1, LEUKOTRIENE C4 & LEUKOTRIENES C 1983-93
History Note: 94; was see SRS-A 1983-93; LEUKOTRIENE C1 & LEUKOTRIENES C were see SRS-A 1983-93
DeCS ID: 31350
Unique ID: D017997
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/06/04
Revision Date: 2015/06/08
Leukotriene C4 - Preferred
Concept UI M0027176
Scope note The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)
Preferred term Leukotriene C4
Entry term(s) LTC4
Leukotriene C 4
Leukotriene C-4
Leukotrienes C - Broader
Concept UI M0027177
Preferred term Leukotrienes C
Entry term(s) Leukotriene C
Leukotriene C1 - Related but not broader or narrower
Concept UI M0027178
Preferred term Leukotriene C1
Entry term(s) Leukotriene C 1
Leukotriene C-1



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