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Descriptor English: Electroporation
Descriptor Spanish: Electroporación
Descriptor electroporación
Scope note: Técnica en la que impulsos eléctricos de intensidad en kilovoltios por centímetro y de una duración entre microsegundos y milisegundos, causa una pérdida temporal de la semipermeabilidad de las MEMBRANAS CELULARES provocando dispersión iónica, escape de metabolitos y una mayor captación por parte de las células de los fármacos, sondas moleculares, y ADN. Algunas aplicaciones de la electroporación son la introducción de plásmidos o ADN extraño en células vivas para transfección, fusión de células para preparar hibridomas, e inserción de proteínas en las membranas celulares.
Descriptor Portuguese: Eletroporação
Descriptor French: Électroporation
Entry term(s): Electropermeabilisation
Tree number(s): E05.200.500.454
E05.242.448
E05.301.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018274
Scope note: A technique in which electric pulses of intensity in kilovolts per centimeter and of microsecond-to-millisecond duration cause a temporary loss of the semipermeability of CELL MEMBRANES, thus leading to ion leakage, escape of metabolites, and increased uptake by cells of drugs, molecular probes, and DNA.
Allowable Qualifiers: CL classification
EC economics
ES ethics
HI history
IS instrumentation
MT methods
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Public MeSH Note: 94
History Note: 94
DeCS ID: 31491
Unique ID: D018274
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/06/03
Revision Date: 2015/06/02
Electroporation - Preferred
Concept UI M0027505
Scope note A technique in which electric pulses of intensity in kilovolts per centimeter and of microsecond-to-millisecond duration cause a temporary loss of the semipermeability of CELL MEMBRANES, thus leading to ion leakage, escape of metabolites, and increased uptake by cells of drugs, molecular probes, and DNA.
Preferred term Electroporation
Entry term(s) Electropermeabilisation



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