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Descriptor English: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Descriptor Spanish: Ácido alfa-Amino-3-hidroxi-5-metil-4-isoxazol Propiónico
Descriptor ácido alfa-amino-3-hidroxi-5-metil-4-isoxazolepropiónico
Entry term(s) AAMP
AMPA
Scope note: Homólogo del ACIDO IBOTÉNICO y agonista del glutamato. Este compuesto es el agonista que define el subtipo de AMPA de los receptores de glutamato (RECEPTORES AMPA). Ha sido utilizado como agente de imagen por radionúclidos, pero se utiliza más comúnmente como herramienta de investigación en estudios de biología celular.
Descriptor Portuguese: Ácido alfa-Amino-3-hidroxi-5-metil-4-isoxazol Propiônico
Descriptor French: AMPA
Entry term(s): AMPA
AMPA, (+-)-Isomer
AMPA, (R)-Isomer
AMPA, (R)-Isomer, Monohydrobromide
AMPA, (S)-Isomer
AMPA, (S)-Isomer, Monohydrobromide
alpha Amino 3 hydroxy 5 methyl 4 isoxazolepropionic Acid
Tree number(s): D03.383.129.385.025
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018350
Scope note: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Excitatory Amino Acid Agonists
Registry Number: 77521-29-0
CAS Type 1 Name: 4-Isoxazolepropanoic acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo-
Previous Indexing: Ibotenic Acid/analogs & derivatives (1980-1993)
Public MeSH Note: 94; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID was indexed under IBOTENIC ACID/analogs & derivatives 1980-93
Online Note: use ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID (NM) to search ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID 1980-93
History Note: 94; was ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID (NM) 1980-93
Related: Receptors, AMPA MeSH
DeCS ID: 31662
Unique ID: D018350
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/06/18
Revision Date: 2016/05/27
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - Preferred
Concept UI M0027584
Scope note An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Preferred term alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Entry term(s) AMPA
alpha Amino 3 hydroxy 5 methyl 4 isoxazolepropionic Acid
AMPA, (R)-Isomer - Narrower
Concept UI M0329160
Preferred term AMPA, (R)-Isomer
AMPA, (S)-Isomer - Narrower
Concept UI M0329159
Preferred term AMPA, (S)-Isomer
AMPA, (S)-Isomer, Monohydrobromide - Narrower
Concept UI M0329162
Preferred term AMPA, (S)-Isomer, Monohydrobromide
AMPA, (+-)-Isomer - Narrower
Concept UI M0329158
Preferred term AMPA, (+-)-Isomer
AMPA, (R)-Isomer, Monohydrobromide - Narrower
Concept UI M0329161
Preferred term AMPA, (R)-Isomer, Monohydrobromide



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