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Descriptor English: Paliperidone Palmitate
Descriptor Spanish: Palmitato de Paliperidona
Descriptor Portuguese: Palmitato de Paliperidona
Descriptor French: Palmitate de palipéridone
Entry term(s): 3-(2-(4-(6-fluoro-3-(1,2-benzisoxazolyl))-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one
9 Hydroxy risperidone
9 Hydroxyrisperidone
9 OH risperidone
9-Hydroxy-risperidone
9-Hydroxyrisperidone
9-OH-risperidone
Invega
Invega Sustenna
Paliperidone
Palmitate, Paliperidone
R 76477
R-76477
R76477
Sustenna, Invega
Tree number(s): D03.383.129.385.650
D03.383.742.592
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068882
Scope note: A benzisoxazole derivative and active metabolite of RISPERIDONE that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST and SEROTONIN 5-HT2 RECEPTOR ANTAGONIST. It is an ANTIPSYCHOTIC AGENT used in the treatment of SCHIZOPHRENIA.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antipsychotic Agents
Serotonin 5-HT2 Receptor Antagonists
Dopamine D2 Receptor Antagonists
Registry Number: R8P8USM8FR
Public MeSH Note: 2016; PALIPERIDONE was indexed under PYRIMIDINES and ISOXAZOLES, 1993-2015; PALIPERIDONE PALMITATE was indexed under ISOXAZOLES and PALMITATE 2010-2015.
History Note: 2016 (1993)
DeCS ID: 55917
Unique ID: D000068882
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/06
Revision Date: 2016/05/31
Paliperidone Palmitate - Preferred
Concept UI M0546009
Scope note A benzisoxazole derivative and active metabolite of RISPERIDONE that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST and SEROTONIN 5-HT2 RECEPTOR ANTAGONIST. It is an ANTIPSYCHOTIC AGENT used in the treatment of SCHIZOPHRENIA.
Preferred term Paliperidone Palmitate
Entry term(s) Palmitate, Paliperidone
Paliperidone - Narrower
Concept UI M0211957
Preferred term Paliperidone
Entry term(s) 3-(2-(4-(6-fluoro-3-(1,2-benzisoxazolyl))-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one
9 Hydroxy risperidone
9 Hydroxyrisperidone
9 OH risperidone
9-Hydroxy-risperidone
9-Hydroxyrisperidone
9-OH-risperidone
Invega - Narrower
Concept UI M0505003
Preferred term Invega
Invega Sustenna - Narrower
Concept UI M000604030
Preferred term Invega Sustenna
Entry term(s) Sustenna, Invega
R 76477 - Narrower
Concept UI M0211960
Preferred term R 76477
Entry term(s) R-76477
R76477



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