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Descriptor English: PrPSc Proteins
Descriptor Spanish: Proteínas PrPSc
Descriptor proteínas PrPSc
Entry term(s) agente scrapie
scrapie PrP
Scope note: Isoforma anormal de las PROTEÍNAS PRIÓNICAS que se produce por la modificación postranslacional de la proteína priónica celular (PROTEÍNAS PRPC). Las PrPSc son proteínas específicas de enfermedades que se encuentran en ciertas enfermedades neurodegenerativas de humanos y animales (ENFERMEDADES POR PRIONES).
Descriptor Portuguese: Proteínas PrPSc
Descriptor French: Protéines PrPSc
Entry term(s): HaSp 33-37
PrP (CJD)
PrP (GSS)
PrP 33-35
PrP res
PrP-res
Scrapie Agent
Scrapie HaSp33-37 Protein
Scrapie PrP
Scrapie PrP 33-35
Scrapie Virus
Sp 33-35
Tree number(s): D12.776.785.340.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018620
Scope note: Abnormal isoform of PRION PROTEINS resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES).
Annotation: PrPSc stands for PRion Protein SCrapie; do not confuse with PRPC PROTEINS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
PY pathogenicity
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Prions (1992-1994)
Viral Proteins (1989-1991)
Public MeSH Note: 95; SCRAPIE AGENT was see PRIONS 1992-94, was heading 1987-91, was SCRAPIE PRION 1986, was SCRAPIE VIRUS 1966-85; SCRAPIE PRP was indexed under PRIONS 1992-94 & VIRAL PROTEINS 1989-91; SCRAPIE VIRUS was see PRIONS 1992-94, was see SCRAPIE AGENT 1987-91, was see SCRAPIE PRION 1986, was heading 1966-85; RIDA VIRUS was see SCRAPIE AGENT 1976-91
Online Note: use PRIONS to search SCRAPIE AGENT, SCRAPIE PRION, & SCRAPIE VIRUS 1966-94, and RIDA VIRUS 1976-91; use PRPSC PROTEINS (NM) to search SCRAPIE PRP 1988-94
History Note: 95; SCRAPIE AGENT was see PRIONS 1992-94, was heading 1987-91, was SCRAPIE PRION 1986, was SCRAPIE VIRUS 1966-85; SCRAPIE PRP was NM 1988-94; SCRAPIE VIRUS was see PRIONS 1992-94, was see SCRAPIE AGENT 1987-91, was see SCRAPIE PRION 1986, was heading 1966-85; RIDA VIRUS was see SCRAPIE AGENT 1976-91
Entry Version: PRPSC
DeCS ID: 32059
Unique ID: D018620
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1995/01/01
Date of Entry: 1994/04/16
Revision Date: 2016/06/13
PrPSc Proteins - Preferred
Concept UI M0027906
Scope note Abnormal isoform of PRION PROTEINS resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES).
Preferred term PrPSc Proteins
Entry term(s) PrP 33-35
PrP res
PrP-res
Scrapie PrP
Scrapie PrP 33-35
Sp 33-35
Scrapie HaSp33-37 Protein - Narrower
Concept UI M0027907
Preferred term Scrapie HaSp33-37 Protein
Entry term(s) HaSp 33-37
PrP (CJD) - Narrower
Concept UI M0027908
Preferred term PrP (CJD)
Scrapie Agent - Related but not broader or narrower
Concept UI M0027905
Preferred term Scrapie Agent
Entry term(s) Scrapie Virus
PrP (GSS) - Narrower
Concept UI M0027909
Preferred term PrP (GSS)



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