| Descriptor English: | Prion Proteins | ||||||
| Descriptor Spanish: |
Proteínas Priónicas
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| Descriptor Portuguese: | Proteínas Priônicas | ||||||
| Descriptor French: | Protéines prion | ||||||
| Entry term(s): |
AltPrP Alternative Prion Protein Antigen, CD230 CD230 Antigen Creutzfeldt Jakob Disease Protein Creutzfeldt-Jakob Disease Protein Fatal Familial Insomnia Protein Major Prion Protein PrP Proteins Prion Protein Prion Protein, Alternative Prion Protein, Major |
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| Tree number(s): |
D12.776.395.550.448.600 D12.776.543.484.500.625 D12.776.543.550.418.600 D12.776.785.340 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000072002 | ||||||
| Scope note: | Membrane glycosylphosphatidylinositol-anchored glycoproteins that may aggregate into rod-like structures. The prion protein (PRNP) gene is characterized by five TANDEM REPEAT SEQUENCES that encode a highly unstable protein region of five octapeptide repeats. Mutations in the repeat region and elsewhere in this gene are associated with CREUTZFELDT-JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GERSTMANN-STRAUSSLER DISEASE; Huntington disease-like 1, and KURU. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Prions (2006-2016) |
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| Public MeSH Note: | 2017; for PRION PROTEINS see PRIONS 1991-2016 |
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| History Note: | 2017: for PRION PROTEINS use PRIONS 1991-2016 |
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| DeCS ID: | 56625 | ||||||
| Unique ID: | D000072002 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Prion Proteins
- Preferred
Alternative Prion Protein
- Related but not broader or narrower
| Concept UI |
M000616231 |
| Scope note | Membrane glycosylphosphatidylinositol-anchored glycoproteins that may aggregate into rod-like structures. The prion protein (PRNP) gene is characterized by five TANDEM REPEAT SEQUENCES that encode a highly unstable protein region of five octapeptide repeats. Mutations in the repeat region and elsewhere in this gene are associated with CREUTZFELDT-JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GERSTMANN-STRAUSSLER DISEASE; Huntington disease-like 1, and KURU. |
| Preferred term | Prion Proteins |
| Entry term(s) |
Antigen, CD230 CD230 Antigen Creutzfeldt Jakob Disease Protein Creutzfeldt-Jakob Disease Protein Fatal Familial Insomnia Protein Major Prion Protein PrP Proteins Prion Protein Prion Protein, Major |
| Concept UI |
M000616233 |
| Scope note | An overlapping open reading frame within the PRNP gene that encodes a protein which is smaller and structurally unrelated to major prion protein. |
| Preferred term | Alternative Prion Protein |
| Entry term(s) |
AltPrP Prion Protein, Alternative |
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